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TRAPPC12 TRAPPC12 RAB3IP RAB3IP TRAPPC11 TRAPPC11 TRAPPC2 TRAPPC2 TRAPPC6B TRAPPC6B TRAPPC10 TRAPPC10 TRAPPC6A TRAPPC6A TRAPPC4 TRAPPC4 TRAPPC3 TRAPPC3 TRAPPC8 TRAPPC8 TRAPPC5 TRAPPC5 RAB33A RAB33A TRAPPC2P1 TRAPPC2P1 TRAPPC1 TRAPPC1 BET3L BET3L RAB43 RAB43 RABIF RABIF UBC UBC RABL6 RABL6 RAB1A RAB1A RAB33B RAB33B RAB1B RAB1B RAB19 RAB19 TBC1D22B TBC1D22B USO1 USO1 TBC1D22A TBC1D22A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
TRAPPC6Atrafficking protein particle complex 6A; May play a role in vesicular transport during the biogenesis of melanosomes (By similarity) (173 aa)
RAB33ARAB33A, member RAS oncogene family (237 aa)
TRAPPC8trafficking protein particle complex 8; May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage (1435 aa)
TRAPPC10trafficking protein particle complex 10; May play a role in vesicular transport from endoplasmic reticulum to Golgi (1259 aa)
TRAPPC1trafficking protein particle complex 1; May play a role in vesicular transport from endoplasmic reticulum to Golgi (145 aa)
RAB33BRAB33B, member RAS oncogene family; Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It is involved in autophagy, acting as a modulator of autophagosome formation (229 aa)
RAB1BRAB1B, member RAS oncogene family; Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments (201 aa)
TRAPPC5trafficking protein particle complex 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi (188 aa)
RAB43RAB43, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport o [...] (212 aa)
TRAPPC12trafficking protein particle complex 12; May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage (735 aa)
TRAPPC6Btrafficking protein particle complex 6B; May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity) (158 aa)
TRAPPC11trafficking protein particle complex 11 (1133 aa)
TBC1D22ATBC1 domain family, member 22A (517 aa)
UBCubiquitin C (685 aa)
RAB19RAB19, member RAS oncogene family (217 aa)
RABIFRAB interacting factor; Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1 and RAB3A, but is less active on these proteins than on the SEC4 protein. Might play a general role in vesicular transport (123 aa)
BET3LBET3 like (S. cerevisiae); May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity) (181 aa)
RABL6RAB, member RAS oncogene family-like 6 (730 aa)
TRAPPC3trafficking protein particle complex 3; May play a role in vesicular transport from endoplasmic reticulum to Golgi (180 aa)
TBC1D22BTBC1 domain family, member 22B; May act as a GTPase-activating protein for Rab family protein(s) (By similarity) (505 aa)
RAB1ARAB1A, member RAS oncogene family; Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity (205 aa)
TRAPPC2trafficking protein particle complex 2; Prevents transcriptional repression and induction of cell death by ENO1 (By similarity). May play a role in vesicular transport from endoplasmic reticulum to Golgi (174 aa)
TRAPPC4trafficking protein particle complex 4; May play a role in vesicular transport from endoplasmic reticulum to Golgi (219 aa)
USO1USO1 vesicle docking protein homolog (yeast); General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity) (971 aa)
TRAPPC2P1trafficking protein particle complex 2 pseudogene 1; Prevents transcriptional repression and induction of cell death by ENO1. May play a role in vesicular transport from endoplasmic reticulum to Golgi (140 aa)
RAB3IPRAB3A interacting protein (rabin3) (476 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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