node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP13A2 | LMAN2 | ENSP00000327214 | ENSP00000303366 | ATPase type 13A2; May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity | lectin, mannose-binding 2; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity) | 0.418 |
ATP13A2 | UBC | ENSP00000327214 | ENSP00000344818 | ATPase type 13A2; May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity | ubiquitin C | 0.890 |
ATP4A | UBC | ENSP00000262623 | ENSP00000344818 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | ubiquitin C | 0.692 |
ATP4A | UBL4A | ENSP00000262623 | ENSP00000358674 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | ubiquitin-like 4A; Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40- it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting | 0.518 |
LMAN2 | ATP13A2 | ENSP00000303366 | ENSP00000327214 | lectin, mannose-binding 2; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity) | ATPase type 13A2; May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity | 0.418 |
LMAN2 | UBC | ENSP00000303366 | ENSP00000344818 | lectin, mannose-binding 2; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity) | ubiquitin C | 0.895 |
MAPK9 | UBC | ENSP00000389338 | ENSP00000344818 | mitogen-activated protein kinase 9 | ubiquitin C | 0.804 |
SUPT5H | UBC | ENSP00000404029 | ENSP00000344818 | suppressor of Ty 5 homolog (S. cerevisiae); Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promot [...] | ubiquitin C | 0.938 |
TP53BP1 | UBC | ENSP00000371475 | ENSP00000344818 | tumor protein p53 binding protein 1; Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation | ubiquitin C | 0.743 |
UBC | ATP13A2 | ENSP00000344818 | ENSP00000327214 | ubiquitin C | ATPase type 13A2; May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity | 0.890 |
UBC | ATP4A | ENSP00000344818 | ENSP00000262623 | ubiquitin C | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | 0.692 |
UBC | LMAN2 | ENSP00000344818 | ENSP00000303366 | ubiquitin C | lectin, mannose-binding 2; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity) | 0.895 |
UBC | MAPK9 | ENSP00000344818 | ENSP00000389338 | ubiquitin C | mitogen-activated protein kinase 9 | 0.804 |
UBC | SUPT5H | ENSP00000344818 | ENSP00000404029 | ubiquitin C | suppressor of Ty 5 homolog (S. cerevisiae); Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promot [...] | 0.938 |
UBC | TP53BP1 | ENSP00000344818 | ENSP00000371475 | ubiquitin C | tumor protein p53 binding protein 1; Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation | 0.743 |
UBC | UBL4A | ENSP00000344818 | ENSP00000358674 | ubiquitin C | ubiquitin-like 4A; Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40- it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting | 0.960 |
UBL4A | ATP4A | ENSP00000358674 | ENSP00000262623 | ubiquitin-like 4A; Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40- it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | 0.518 |
UBL4A | UBC | ENSP00000358674 | ENSP00000344818 | ubiquitin-like 4A; Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40- it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting | ubiquitin C | 0.960 |