node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DYRK1A | KIAA0232 | ENSP00000381932 | ENSP00000303928 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 | KIAA0232 | 0.461 |
DYRK1A | YWHAE | ENSP00000381932 | ENSP00000264335 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.887 |
DYRK1A | YWHAZ | ENSP00000381932 | ENSP00000309503 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.750 |
DYRK1B | KIAA0232 | ENSP00000312789 | ENSP00000303928 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments | KIAA0232 | 0.461 |
DYRK1B | YWHAE | ENSP00000312789 | ENSP00000264335 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.725 |
DYRK1B | YWHAZ | ENSP00000312789 | ENSP00000309503 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.733 |
KIAA0232 | DYRK1A | ENSP00000303928 | ENSP00000381932 | KIAA0232 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 | 0.461 |
KIAA0232 | DYRK1B | ENSP00000303928 | ENSP00000312789 | KIAA0232 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments | 0.461 |
YWHAE | DYRK1A | ENSP00000264335 | ENSP00000381932 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 | 0.887 |
YWHAE | DYRK1B | ENSP00000264335 | ENSP00000312789 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments | 0.725 |
YWHAE | YWHAZ | ENSP00000264335 | ENSP00000309503 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.999 |
YWHAZ | DYRK1A | ENSP00000309503 | ENSP00000381932 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 | 0.750 |
YWHAZ | DYRK1B | ENSP00000309503 | ENSP00000312789 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments | 0.733 |
YWHAZ | YWHAE | ENSP00000309503 | ENSP00000264335 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.999 |