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STRINGSTRING
SURF4 SURF4 VKORC1 VKORC1 CHPT1 CHPT1 CEPT1 CEPT1 SCAMP5 SCAMP5 TMEM33 TMEM33 SCAMP3 SCAMP3 ATP9B ATP9B CREB3L1 CREB3L1 SCAMP2 SCAMP2 DHRS7B DHRS7B OSTC OSTC UBC UBC JAGN1 JAGN1 SLC35F5 SLC35F5 CBR3 CBR3 CCDC155 CCDC155 SCAMP4 SCAMP4 CLEC7A CLEC7A ATP9A ATP9A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
CHPT1choline phosphotransferase 1 (406 aa)
SLC35F5solute carrier family 35, member F5; Putative solute transporter (Potential) (523 aa)
SCAMP2secretory carrier membrane protein 2; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface (329 aa)
CBR3carbonyl reductase 3; Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro) (277 aa)
CLEC7AC-type lectin domain family 7, member A (247 aa)
JAGN1jagunal homolog 1 (Drosophila); May be required for endoplasmic reticulum organization (By similarity) (183 aa)
SCAMP3secretory carrier membrane protein 3; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface (347 aa)
SCAMP4secretory carrier membrane protein 4; Probably involved in membrane protein trafficking (By similarity) (229 aa)
ATP9AATPase, class II, type 9A (1047 aa)
UBCubiquitin C (685 aa)
CEPT1choline/ethanolamine phosphotransferase 1; Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity (416 aa)
OSTColigosaccharyltransferase complex subunit (149 aa)
SCAMP5secretory carrier membrane protein 5; Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway (235 aa)
SURF4surfeit 4; May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi (269 aa)
VKORC1vitamin K epoxide reductase complex, subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K (163 aa)
DHRS7Bdehydrogenase/reductase (SDR family) member 7B; Putative oxidoreductase (Potential) (325 aa)
ATP9BATPase, class II, type 9B (1147 aa)
CCDC155coiled-coil domain containing 155; May be involved in meiotic chromosome dynamics and homolog pairing (By similarity) (562 aa)
TMEM33transmembrane protein 33 (247 aa)
CREB3L1cAMP responsive element binding protein 3-like 1; Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity) (519 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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