Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | EMC9 | ER membrane protein complex subunit 9 (208 aa) | ||
 | EMC2 | ER membrane protein complex subunit 2 (297 aa) | ||
 | MPV17 | MpV17 mitochondrial inner membrane protein; Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance (176 aa) | ||
 | EMC3 | ER membrane protein complex subunit 3 (261 aa) | ||
 | EMC6 | ER membrane protein complex subunit 6 (110 aa) | ||
 | MTX2 | metaxin 2; Involved in transport of proteins into the mitochondrion (263 aa) | ||
 | EMC8 | ER membrane protein complex subunit 8 (210 aa) | ||
 | EMC7 | ER membrane protein complex subunit 7 (242 aa) | ||
 | CORO1C | coronin, actin binding protein, 1C; May be involved in cytokinesis, motility, and signal transduction (By similarity) (474 aa) | ||
 | EMC4 | ER membrane protein complex subunit 4; May mediate anti-apoptotic activity (183 aa) | ||
 | NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (186 aa) | ||
 | MMGT1 | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) (131 aa) | ||
 | MRPL1 | mitochondrial ribosomal protein L1 (325 aa) | ||
 | NDUFA12 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (145 aa) | ||
 | EMC10 | ER membrane protein complex subunit 10 (262 aa) | ||
 | DHX15 | DEAH (Asp-Glu-Ala-His) box polypeptide 15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA (By similarity) (795 aa) | ||
 | UBC | ubiquitin C (685 aa) | ||
 | ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter (1545 aa) | ||
 | TM9SF2 | transmembrane 9 superfamily member 2; In the intracellular compartments, may function as a channel or small molecule transporter (663 aa) | ||
 | FLOT2 | flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function (428 aa) | ||
 | ELAVL1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro (326 aa) | ||
 | EMC1 | ER membrane protein complex subunit 1 (993 aa) | ||
 | OCIAD2 | OCIA domain containing 2 (154 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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