Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components- 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (1023 aa) | ||
 | MRPL32 | mitochondrial ribosomal protein L32 (188 aa) | ||
 | MRPL51 | mitochondrial ribosomal protein L51 (128 aa) | ||
 | MRPL44 | mitochondrial ribosomal protein L44; Component of the 39S subunit of mitochondrial ribosome (332 aa) | ||
 | MRPS9 | mitochondrial ribosomal protein S9 (396 aa) | ||
 | MRPL15 | mitochondrial ribosomal protein L15 (296 aa) | ||
 | TMEM177 | transmembrane protein 177 (311 aa) | ||
 | MRPL49 | mitochondrial ribosomal protein L49 (166 aa) | ||
 | MRPL16 | mitochondrial ribosomal protein L16; Component of the large subunit of mitochondrial ribosome (251 aa) | ||
 | TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae); Required during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) (804 aa) | ||
 | MRPL39 | mitochondrial ribosomal protein L39 (353 aa) | ||
 | MRPL13 | mitochondrial ribosomal protein L13 (178 aa) | ||
 | MRPL38 | mitochondrial ribosomal protein L38 (380 aa) | ||
 | MRPL11 | mitochondrial ribosomal protein L11 (192 aa) | ||
 | MRP63 | mitochondrial ribosomal protein 63 (102 aa) | ||
 | MRPL40 | mitochondrial ribosomal protein L40 (206 aa) | ||
 | MRPL30 | mitochondrial ribosomal protein L30 (161 aa) | ||
 | MRPL52 | mitochondrial ribosomal protein L52 (123 aa) | ||
 | MRPL37 | mitochondrial ribosomal protein L37 (423 aa) | ||
 | MRPL21 | mitochondrial ribosomal protein L21 (205 aa) | ||
 | MRPL9 | mitochondrial ribosomal protein L9 (267 aa) | ||
 | MRPL14 | mitochondrial ribosomal protein L14; Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable) (145 aa) | ||
 | MRPL50 | mitochondrial ribosomal protein L50 (158 aa) | ||
 | MRPL23 | mitochondrial ribosomal protein L23 (153 aa) | ||
 | MRPL19 | mitochondrial ribosomal protein L19 (292 aa) | ||
 | C2orf15 | chromosome 2 open reading frame 15 (161 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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