Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | OR1E2 | olfactory receptor, family 1, subfamily E, member 2; Odorant receptor (Potential) (323 aa) | ||
 | NEDD8 | neural precursor cell expressed, developmentally down-regulated 8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C- APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (81 aa) | ||
 | NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (124 aa) | ||
 | OR4K1 | olfactory receptor, family 4, subfamily K, member 1; Odorant receptor (Potential) (311 aa) | ||
 | OR3A3 | olfactory receptor, family 3, subfamily A, member 3; Odorant receptor (Potential) (321 aa) | ||
 | OR5A2 | olfactory receptor, family 5, subfamily A, member 2; Odorant receptor (Potential) (324 aa) | ||
 | OR52W1 | olfactory receptor, family 52, subfamily W, member 1; Odorant receptor (Potential) (320 aa) | ||
 | OR4S2 | olfactory receptor, family 4, subfamily S, member 2; Odorant receptor (Potential) (311 aa) | ||
 | OR4F21 | olfactory receptor, family 4, subfamily F, member 21; Odorant receptor (Potential) (312 aa) | ||
 | OR52E4 | olfactory receptor, family 52, subfamily E, member 4; Odorant receptor (Potential) (312 aa) | ||
 | OR51H1P | olfactory receptor, family 51, subfamily H, member 1 pseudogene; Odorant receptor (Potential) (302 aa) | ||
 | OR52N4 | olfactory receptor, family 52, subfamily N, member 4; Odorant receptor (Potential) (321 aa) | ||
 | OR8H2 | olfactory receptor, family 8, subfamily H, member 2; Odorant receptor (Potential) (312 aa) | ||
 | OR4A15 | olfactory receptor, family 4, subfamily A, member 15; Odorant receptor (Potential) (344 aa) | ||
 | OR4M2 | olfactory receptor, family 4, subfamily M, member 2; Odorant receptor (Potential) (313 aa) | ||
 | OR10T2 | olfactory receptor, family 10, subfamily T, member 2; Odorant receptor (Potential) (314 aa) | ||
 | OR6N1 | olfactory receptor, family 6, subfamily N, member 1; Odorant receptor (Potential) (312 aa) | ||
 | OR1J2 | olfactory receptor, family 1, subfamily J, member 2; Odorant receptor (Potential) (313 aa) | ||
 | OR6C74 | olfactory receptor, family 6, subfamily C, member 74; Odorant receptor (Potential) (312 aa) | ||
 | OR5H1 | olfactory receptor, family 5, subfamily H, member 1; Odorant receptor (Potential) (313 aa) | ||
 | OR2T4 | olfactory receptor, family 2, subfamily T, member 4; Odorant receptor (Potential) (348 aa) | ||
 | OR10R2 | olfactory receptor, family 10, subfamily R, member 2; Odorant receptor (Potential) (335 aa) | ||
 | OR5D16 | olfactory receptor, family 5, subfamily D, member 16; Odorant receptor (Potential) (328 aa) | ||
 | OR1A2 | olfactory receptor, family 1, subfamily A, member 2; Odorant receptor (Potential) (309 aa) | ||
 | OR5K1 | olfactory receptor, family 5, subfamily K, member 1; Odorant receptor (Potential) (308 aa) | ||
 | OR6C4 | olfactory receptor, family 6, subfamily C, member 4; Odorant receptor (Potential) (309 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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