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YKT6 | YKT6 v-SNARE homolog (S. cerevisiae); Vesicular soluble NSF attachment protein receptor (v- SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity (198 aa) | |||
GOLT1B | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex (138 aa) | |||
TGFBRAP1 | transforming growth factor, beta receptor associated protein 1; Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2 (860 aa) | |||
ARL1 | ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus (181 aa) | |||
RAB36 | RAB36, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) (333 aa) | |||
SEC22C | SEC22 vesicle trafficking protein homolog C (S. cerevisiae); May be involved in vesicle transport between the ER and the Golgi complex (303 aa) | |||
RAB41 | RAB41, member RAS oncogene family (221 aa) | |||
RAB6B | RAB6B, member RAS oncogene family; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells (208 aa) | |||
STX5 | syntaxin 5; Mediates endoplasmic reticulum to Golgi transport (By similarity) (355 aa) | |||
UBB | ubiquitin B (229 aa) | |||
COG8 | component of oligomeric golgi complex 8; Required for normal Golgi function (By similarity) (612 aa) | |||
GOLT1A | golgi transport 1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex (132 aa) | |||
SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae); May be involved in vesicle transport between the ER and the Golgi complex (By similarity) (307 aa) | |||
SFT2D3 | SFT2 domain containing 3; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) (215 aa) | |||
RAB6A | RAB6A, member RAS oncogene family; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity (208 aa) | |||
UBC | ubiquitin C (685 aa) | |||
STX16 | syntaxin 16 (325 aa) | |||
VTI1A | vesicle transport through interaction with t-SNAREs homolog 1A (yeast); V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with [...] (217 aa) | |||
RAB6C | RAB6C, member RAS oncogene family; May be involved in the regulation of centrosome duplication and cell cycle progression (254 aa) | |||
COG6 | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) (657 aa) | |||
RAB34 | RAB34, member RAS oncogene family; Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes (316 aa) | |||
KIAA1432 | KIAA1432 (1423 aa) | |||
VTI1B | vesicle transport through interaction with t-SNAREs homolog 1B (yeast); V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence (232 aa) | |||
ENSG00000260371 | Uncharacterized protein (156 aa) | |||
ENSG00000254995 | STX16-NPEPL1 readthrough (non-protein coding) (382 aa) | |||
ENSG00000261576 | Uncharacterized protein (164 aa) |