adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

bradykinin receptor B1; This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

complement component 5; Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

chemokine (C-X-C motif) ligand 6; Chemotactic for neutrophil granulocytes

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

chemokine (C-X-C motif) receptor 7; Receptor for chemokines CXCL12/SDF1 and CXCL11. Does not elicit classical chemokine receptor signaling; chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Acts as a scavenger for CXCL12/SDF1 and, to a lesser extent, for CXCL11. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, [...]

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

dopamine receptor D4

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

guanine nucleotide binding protein (G protein), gamma 11; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

guanine nucleotide binding protein (G protein), gamma 13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

glutamate receptor, metabotropic 6; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

heme binding protein 1; May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N- methylprotoporphyrin with similar affinities

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

melanocortin 3 receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

NME/NM23 nucleoside diphosphate kinase 1; Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3’-5’ exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein- coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

NME/NM23 nucleoside diphosphate kinase 3; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

NME/NM23 nucleoside diphosphate kinase 4; Major role in the synthesis of nucleoside triphosphates other than ATP (By similarity)

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

opioid receptor, delta 1; Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

prodynorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity)

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity)

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the low [...]

adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity)

pancreatic polypeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions