node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP6V1A | TXNDC5 | ENSP00000273398 | ENSP00000369081 | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | thioredoxin domain containing 5 (endoplasmic reticulum); Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity) | 0.654 |
ATP6V1A | UBC | ENSP00000273398 | ENSP00000344818 | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | ubiquitin C | 0.978 |
ATP6V1A | ZNF706 | ENSP00000273398 | ENSP00000311768 | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | zinc finger protein 706 | 0.909 |
C4orf27 | UBC | ENSP00000406598 | ENSP00000344818 | chromosome 4 open reading frame 27 | ubiquitin C | 0.620 |
CCS | UBC | ENSP00000436318 | ENSP00000344818 | copper chaperone for superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) | ubiquitin C | 0.723 |
CIT | UBC | ENSP00000376306 | ENSP00000344818 | citron (rho-interacting, serine/threonine kinase 21); Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2 | ubiquitin C | 0.620 |
CIT | ZNF706 | ENSP00000376306 | ENSP00000311768 | citron (rho-interacting, serine/threonine kinase 21); Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2 | zinc finger protein 706 | 0.664 |
NUP54 | SNRPG | ENSP00000264883 | ENSP00000272348 | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | small nuclear ribonucleoprotein polypeptide G; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5 | 0.900 |
NUP54 | UBC | ENSP00000264883 | ENSP00000344818 | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | ubiquitin C | 0.952 |
ORC5 | UBC | ENSP00000297431 | ENSP00000344818 | origin recognition complex, subunit 5; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication | ubiquitin C | 0.972 |
RPS21 | UBC | ENSP00000345957 | ENSP00000344818 | ribosomal protein S21 | ubiquitin C | 0.969 |
SNRPG | NUP54 | ENSP00000272348 | ENSP00000264883 | small nuclear ribonucleoprotein polypeptide G; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5 | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.900 |
SNRPG | UBC | ENSP00000272348 | ENSP00000344818 | small nuclear ribonucleoprotein polypeptide G; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5 | ubiquitin C | 0.861 |
SNRPG | ZNF706 | ENSP00000272348 | ENSP00000311768 | small nuclear ribonucleoprotein polypeptide G; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5 | zinc finger protein 706 | 0.406 |
TXNDC5 | ATP6V1A | ENSP00000369081 | ENSP00000273398 | thioredoxin domain containing 5 (endoplasmic reticulum); Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity) | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.654 |
TXNDC5 | UBC | ENSP00000369081 | ENSP00000344818 | thioredoxin domain containing 5 (endoplasmic reticulum); Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity) | ubiquitin C | 0.846 |
TXNDC5 | ZNF706 | ENSP00000369081 | ENSP00000311768 | thioredoxin domain containing 5 (endoplasmic reticulum); Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity) | zinc finger protein 706 | 0.960 |
UBC | ATP6V1A | ENSP00000344818 | ENSP00000273398 | ubiquitin C | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.978 |
UBC | C4orf27 | ENSP00000344818 | ENSP00000406598 | ubiquitin C | chromosome 4 open reading frame 27 | 0.620 |
UBC | CCS | ENSP00000344818 | ENSP00000436318 | ubiquitin C | copper chaperone for superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) | 0.723 |