node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EXOC2 | UBC | ENSP00000230449 | ENSP00000344818 | exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane | ubiquitin C | 0.880 |
EXOC2 | ZNF598 | ENSP00000230449 | ENSP00000411409 | exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane | zinc finger protein 598 | 0.430 |
FAM57A | GGT7 | ENSP00000312017 | ENSP00000338964 | family with sequence similarity 57, member A | gamma-glutamyltransferase 7; Cleaves glutathione conjugates (By similarity) | 0.989 |
FAM57A | SLC3A2 | ENSP00000312017 | ENSP00000367123 | family with sequence similarity 57, member A | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids [...] | 0.961 |
GGT7 | FAM57A | ENSP00000338964 | ENSP00000312017 | gamma-glutamyltransferase 7; Cleaves glutathione conjugates (By similarity) | family with sequence similarity 57, member A | 0.989 |
GGT7 | SLC3A2 | ENSP00000338964 | ENSP00000367123 | gamma-glutamyltransferase 7; Cleaves glutathione conjugates (By similarity) | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids [...] | 0.489 |
PIN1 | UBC | ENSP00000247970 | ENSP00000344818 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1; Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML [...] | ubiquitin C | 0.889 |
RPS4Y1 | UBC | ENSP00000250784 | ENSP00000344818 | ribosomal protein S4, Y-linked 1 | ubiquitin C | 0.949 |
SLC3A2 | FAM57A | ENSP00000367123 | ENSP00000312017 | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids [...] | family with sequence similarity 57, member A | 0.961 |
SLC3A2 | GGT7 | ENSP00000367123 | ENSP00000338964 | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids [...] | gamma-glutamyltransferase 7; Cleaves glutathione conjugates (By similarity) | 0.489 |
SLC3A2 | UBC | ENSP00000367123 | ENSP00000344818 | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids [...] | ubiquitin C | 0.996 |
UBC | EXOC2 | ENSP00000344818 | ENSP00000230449 | ubiquitin C | exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane | 0.880 |
UBC | PIN1 | ENSP00000344818 | ENSP00000247970 | ubiquitin C | peptidylprolyl cis/trans isomerase, NIMA-interacting 1; Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML [...] | 0.889 |
UBC | RPS4Y1 | ENSP00000344818 | ENSP00000250784 | ubiquitin C | ribosomal protein S4, Y-linked 1 | 0.949 |
UBC | SLC3A2 | ENSP00000344818 | ENSP00000367123 | ubiquitin C | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids [...] | 0.996 |
UBC | ZNF598 | ENSP00000344818 | ENSP00000411409 | ubiquitin C | zinc finger protein 598 | 0.960 |
ZNF598 | EXOC2 | ENSP00000411409 | ENSP00000230449 | zinc finger protein 598 | exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane | 0.430 |
ZNF598 | UBC | ENSP00000411409 | ENSP00000344818 | zinc finger protein 598 | ubiquitin C | 0.960 |