node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD172b | CD7 | ENSP00000454437 | ENSP00000312027 | Uncharacterized protein ; Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK | CD7 molecule; Not yet known | 0.576 |
CD7 | CD172b | ENSP00000312027 | ENSP00000454437 | CD7 molecule; Not yet known | Uncharacterized protein ; Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK | 0.576 |
CD7 | CGB8 | ENSP00000312027 | ENSP00000403649 | CD7 molecule; Not yet known | chorionic gonadotropin, beta polypeptide 8 | 0.996 |
CD7 | CTSL1 | ENSP00000312027 | ENSP00000345344 | CD7 molecule; Not yet known | cathepsin L1; Important for the overall degradation of proteins in lysosomes | 0.614 |
CD7 | LGALS1 | ENSP00000312027 | ENSP00000215909 | CD7 molecule; Not yet known | lectin, galactoside-binding, soluble, 1; May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase | 0.934 |
CD7 | PI4K2A | ENSP00000312027 | ENSP00000359665 | CD7 molecule; Not yet known | phosphatidylinositol 4-kinase type 2 alpha; Together with PI4K2B and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells (By similarity) | 0.576 |
CD7 | PI4KA | ENSP00000312027 | ENSP00000458238 | CD7 molecule; Not yet known | phosphatidylinositol 4-kinase, catalytic, alpha; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate | 0.576 |
CD7 | PIK3R1 | ENSP00000312027 | ENSP00000274335 | CD7 molecule; Not yet known | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.812 |
CD7 | SECTM1 | ENSP00000312027 | ENSP00000269389 | CD7 molecule; Not yet known | secreted and transmembrane 1; May be involved in thymocyte signaling | 0.940 |
CD7 | SIRPG | ENSP00000312027 | ENSP00000305529 | CD7 molecule; Not yet known | signal-regulatory protein gamma; Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T- cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation | 0.576 |
CD7 | SNAP29 | ENSP00000312027 | ENSP00000215730 | CD7 molecule; Not yet known | synaptosomal-associated protein, 29kDa; SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps | 0.574 |
CGB8 | CD7 | ENSP00000403649 | ENSP00000312027 | chorionic gonadotropin, beta polypeptide 8 | CD7 molecule; Not yet known | 0.996 |
CGB8 | SIRPG | ENSP00000403649 | ENSP00000305529 | chorionic gonadotropin, beta polypeptide 8 | signal-regulatory protein gamma; Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T- cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation | 0.996 |
CTSL1 | CD7 | ENSP00000345344 | ENSP00000312027 | cathepsin L1; Important for the overall degradation of proteins in lysosomes | CD7 molecule; Not yet known | 0.614 |
LGALS1 | CD7 | ENSP00000215909 | ENSP00000312027 | lectin, galactoside-binding, soluble, 1; May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase | CD7 molecule; Not yet known | 0.934 |
NFKBIA | PIK3R1 | ENSP00000216797 | ENSP00000274335 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.959 |
PI4K2A | CD7 | ENSP00000359665 | ENSP00000312027 | phosphatidylinositol 4-kinase type 2 alpha; Together with PI4K2B and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells (By similarity) | CD7 molecule; Not yet known | 0.576 |
PI4K2A | PI4KA | ENSP00000359665 | ENSP00000458238 | phosphatidylinositol 4-kinase type 2 alpha; Together with PI4K2B and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells (By similarity) | phosphatidylinositol 4-kinase, catalytic, alpha; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate | 0.809 |
PI4KA | CD7 | ENSP00000458238 | ENSP00000312027 | phosphatidylinositol 4-kinase, catalytic, alpha; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate | CD7 molecule; Not yet known | 0.576 |
PI4KA | PI4K2A | ENSP00000458238 | ENSP00000359665 | phosphatidylinositol 4-kinase, catalytic, alpha; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate | phosphatidylinositol 4-kinase type 2 alpha; Together with PI4K2B and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells (By similarity) | 0.809 |