node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABL2 | CD84 | ENSP00000427562 | ENSP00000312367 | v-abl Abelson murine leukemia viral oncogene homolog 2 | CD84 molecule | 0.573 |
ABL2 | PTPN11 | ENSP00000427562 | ENSP00000340944 | v-abl Abelson murine leukemia viral oncogene homolog 2 | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | 0.454 |
ABL2 | UBC | ENSP00000427562 | ENSP00000344818 | v-abl Abelson murine leukemia viral oncogene homolog 2 | ubiquitin C | 0.751 |
CD84 | ABL2 | ENSP00000312367 | ENSP00000427562 | CD84 molecule | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.573 |
CD84 | PTPN11 | ENSP00000312367 | ENSP00000340944 | CD84 molecule | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | 0.753 |
CD84 | SH2D1A | ENSP00000312367 | ENSP00000360181 | CD84 molecule | SH2 domain containing 1A; Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 | 0.990 |
CD84 | SH2D1B | ENSP00000312367 | ENSP00000356906 | CD84 molecule | SH2 domain containing 1B; Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells | 0.990 |
PTPN11 | ABL2 | ENSP00000340944 | ENSP00000427562 | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.454 |
PTPN11 | CD84 | ENSP00000340944 | ENSP00000312367 | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | CD84 molecule | 0.753 |
PTPN11 | SH2D1A | ENSP00000340944 | ENSP00000360181 | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | SH2 domain containing 1A; Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 | 0.535 |
PTPN11 | SH2D1B | ENSP00000340944 | ENSP00000356906 | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | SH2 domain containing 1B; Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells | 0.511 |
PTPN11 | UBC | ENSP00000340944 | ENSP00000344818 | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | ubiquitin C | 0.978 |
SH2D1A | CD84 | ENSP00000360181 | ENSP00000312367 | SH2 domain containing 1A; Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 | CD84 molecule | 0.990 |
SH2D1A | PTPN11 | ENSP00000360181 | ENSP00000340944 | SH2 domain containing 1A; Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | 0.535 |
SH2D1A | UBC | ENSP00000360181 | ENSP00000344818 | SH2 domain containing 1A; Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 | ubiquitin C | 0.483 |
SH2D1B | CD84 | ENSP00000356906 | ENSP00000312367 | SH2 domain containing 1B; Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells | CD84 molecule | 0.990 |
SH2D1B | PTPN11 | ENSP00000356906 | ENSP00000340944 | SH2 domain containing 1B; Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | 0.511 |
UBC | ABL2 | ENSP00000344818 | ENSP00000427562 | ubiquitin C | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.751 |
UBC | PTPN11 | ENSP00000344818 | ENSP00000340944 | ubiquitin C | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | 0.978 |
UBC | SH2D1A | ENSP00000344818 | ENSP00000360181 | ubiquitin C | SH2 domain containing 1A; Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 | 0.483 |