node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EPB41L1 | UBC | ENSP00000337168 | ENSP00000344818 | erythrocyte membrane protein band 4.1-like 1 | ubiquitin C | 0.483 |
EPB41L2 | EPB41L3 | ENSP00000338481 | ENSP00000341138 | erythrocyte membrane protein band 4.1-like 2 | erythrocyte membrane protein band 4.1-like 3; Critical growth regulator in the pathogenesis of meningiomas | 0.654 |
EPB41L2 | UBC | ENSP00000338481 | ENSP00000344818 | erythrocyte membrane protein band 4.1-like 2 | ubiquitin C | 0.892 |
EPB41L3 | EPB41L2 | ENSP00000341138 | ENSP00000338481 | erythrocyte membrane protein band 4.1-like 3; Critical growth regulator in the pathogenesis of meningiomas | erythrocyte membrane protein band 4.1-like 2 | 0.654 |
EPB41L3 | UBC | ENSP00000341138 | ENSP00000344818 | erythrocyte membrane protein band 4.1-like 3; Critical growth regulator in the pathogenesis of meningiomas | ubiquitin C | 0.621 |
ISG15 | UBC | ENSP00000368699 | ENSP00000344818 | ISG15 ubiquitin-like modifier; Ubiquitin-like protein that is conjugated to intracellular target proteins after IFN-alpha or IFN-beta stimulation. Its enzymatic pathway is partially distinct from that of ubiquitin, differing in substrate specificity and interaction with ligating enzymes. ISG15 conjugation pathway uses a dedicated E1 enzyme, but seems to converge with the Ub conjugation pathway at the level of a specific E2 enzyme. Targets include STAT1, SERPINA3G/SPI2A, JAK1, MAPK3/ERK1, PLCG1, EIF2AK2/PKR, MX1/MxA, and RIG-1. Deconjugated by USP18/UBP43. Shows specific chemotactic act [...] | ubiquitin C | 0.884 |
ISG15 | WWP2 | ENSP00000368699 | ENSP00000348283 | ISG15 ubiquitin-like modifier; Ubiquitin-like protein that is conjugated to intracellular target proteins after IFN-alpha or IFN-beta stimulation. Its enzymatic pathway is partially distinct from that of ubiquitin, differing in substrate specificity and interaction with ligating enzymes. ISG15 conjugation pathway uses a dedicated E1 enzyme, but seems to converge with the Ub conjugation pathway at the level of a specific E2 enzyme. Targets include STAT1, SERPINA3G/SPI2A, JAK1, MAPK3/ERK1, PLCG1, EIF2AK2/PKR, MX1/MxA, and RIG-1. Deconjugated by USP18/UBP43. Shows specific chemotactic act [...] | WW domain containing E3 ubiquitin protein ligase 2 | 0.478 |
LGALS9B | NDUFB10 | ENSP00000315564 | ENSP00000268668 | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | 0.604 |
LGALS9B | PRTFDC1 | ENSP00000315564 | ENSP00000318602 | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | phosphoribosyl transferase domain containing 1; Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage | 0.512 |
LGALS9B | SGTA | ENSP00000315564 | ENSP00000221566 | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity | 0.483 |
LGALS9B | SGTB | ENSP00000315564 | ENSP00000370395 | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity) | 0.483 |
LGALS9B | WWP2 | ENSP00000315564 | ENSP00000348283 | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | WW domain containing E3 ubiquitin protein ligase 2 | 0.551 |
NDUFB10 | LGALS9B | ENSP00000268668 | ENSP00000315564 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | 0.604 |
NDUFB10 | UBC | ENSP00000268668 | ENSP00000344818 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | ubiquitin C | 0.899 |
PRTFDC1 | LGALS9B | ENSP00000318602 | ENSP00000315564 | phosphoribosyl transferase domain containing 1; Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | 0.512 |
PRTFDC1 | UBC | ENSP00000318602 | ENSP00000344818 | phosphoribosyl transferase domain containing 1; Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage | ubiquitin C | 0.620 |
SGTA | LGALS9B | ENSP00000221566 | ENSP00000315564 | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | 0.483 |
SGTA | UBC | ENSP00000221566 | ENSP00000344818 | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity | ubiquitin C | 0.987 |
SGTB | LGALS9B | ENSP00000370395 | ENSP00000315564 | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity) | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) | 0.483 |
SGTB | UBC | ENSP00000370395 | ENSP00000344818 | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity) | ubiquitin C | 0.766 |