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MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6 (246 aa) | |||
TMEM147 | transmembrane protein 147 (224 aa) | |||
TMEM115 | transmembrane protein 115 (351 aa) | |||
TMEM140 | transmembrane protein 140 (185 aa) | |||
ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3; Has a threefold preference for the hydrolysis of ATP over ADP (529 aa) | |||
CLEC7A | C-type lectin domain family 7, member A (247 aa) | |||
SLN | sarcolipin (31 aa) | |||
SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae); May be involved in vesicle transport between the ER and the Golgi complex (By similarity) (307 aa) | |||
EDDM3B | epididymal protein 3B; Possible function in sperm maturation (147 aa) | |||
SYNE4 | spectrin repeat containing, nuclear envelope family member 4; Contributes to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity) (404 aa) | |||
BRICD5 | BRICHOS domain containing 5 (228 aa) | |||
TMEM248 | transmembrane protein 248 (314 aa) | |||
PAQR5 | progestin and adipoQ receptor family member V; Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (330 aa) | |||
OCLN | occludin (522 aa) | |||
KLRG1 | killer cell lectin-like receptor subfamily G, member 1; Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells (189 aa) | |||
CLDN7 | claudin 7; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) (211 aa) | |||
CXCL9 | chemokine (C-X-C motif) ligand 9; Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3 (125 aa) | |||
CD47 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] (323 aa) | |||
C10orf35 | chromosome 10 open reading frame 35 (121 aa) | |||
TSPAN15 | tetraspanin 15 (294 aa) | |||
CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains (542 aa) | |||
KTN1 | kinectin 1 (kinesin receptor); Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin (1357 aa) | |||
ECE2 | endothelin converting enzyme 2; Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta- amyloid peptide accumulation in brain. May also have methyltransferase activity (883 aa) | |||
TMEM182 | transmembrane protein 182 (229 aa) | |||
TMPRSS4 | transmembrane protease, serine 4; Probable protease. Seems to be capable of activating ENaC (By similarity) (437 aa) | |||
DEFB121 | defensin, beta 121; Has antibacterial activity (Potential) (76 aa) |