Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | MRPL32 | mitochondrial ribosomal protein L32 (188 aa) | ||
 | MRPL27 | mitochondrial ribosomal protein L27 (148 aa) | ||
 | MRPL34 | mitochondrial ribosomal protein L34 (92 aa) | ||
 | MRPL4 | mitochondrial ribosomal protein L4 (311 aa) | ||
 | TACO1 | translational activator of mitochondrially encoded cytochrome c oxidase I; Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1 (297 aa) | ||
 | RPL8 | ribosomal protein L8 (257 aa) | ||
 | MSH4 | mutS homolog 4 (E. coli); Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis (936 aa) | ||
 | MSH3 | mutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion- deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resy [...] (1137 aa) | ||
 | RPL26L1 | ribosomal protein L26-like 1 (145 aa) | ||
 | THTPA | thiamine triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP) (230 aa) | ||
 | MRPL17 | mitochondrial ribosomal protein L17 (175 aa) | ||
 | RPL26 | ribosomal protein L26 (145 aa) | ||
 | MRPL33 | mitochondrial ribosomal protein L33 (65 aa) | ||
 | MRPL1 | mitochondrial ribosomal protein L1 (325 aa) | ||
 | GTPBP6 | GTP binding protein 6 (putative) (287 aa) | ||
 | IP6K2 | inositol hexakisphosphate kinase 2 (426 aa) | ||
 | RPLP0 | ribosomal protein, large, P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10 (By similarity) (317 aa) | ||
 | SDF4 | stromal cell derived factor 4 (362 aa) | ||
 | MRPL24 | mitochondrial ribosomal protein L24 (216 aa) | ||
 | RPL10A | ribosomal protein L10a (217 aa) | ||
 | RPL11 | ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) (178 aa) | ||
 | MRTO4 | mRNA turnover 4 homolog (S. cerevisiae); Involved in mRNA turnover and ribosome assembly (By similarity) (239 aa) | ||
 | MRPL2 | mitochondrial ribosomal protein L2 (305 aa) | ||
 | RPL23 | ribosomal protein L23 (140 aa) | ||
 | RPL23A | ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA (By similarity) (156 aa) | ||
 | ENSG00000263809 | KRAB-A domain-containing protein 2 (107 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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