node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL10A1 | COL1A1 | ENSP00000243222 | ENSP00000225964 | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | collagen, type I, alpha 1 | 0.944 |
COL10A1 | COL1A2 | ENSP00000243222 | ENSP00000297268 | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | collagen, type I, alpha 2 | 0.926 |
COL10A1 | COL3A1 | ENSP00000243222 | ENSP00000304408 | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | collagen, type III, alpha 1 | 0.918 |
COL10A1 | LEPRE1 | ENSP00000243222 | ENSP00000296388 | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | leucine proline-enriched proteoglycan (leprecan) 1 | 0.900 |
COL10A1 | LEPREL1 | ENSP00000243222 | ENSP00000316881 | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | leprecan-like 1; Shows prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types II, IV and V (By similarity) | 0.900 |
COL10A1 | P4HB | ENSP00000243222 | ENSP00000327801 | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | prolyl 4-hydroxylase, beta polypeptide; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with [...] | 0.954 |
COL1A1 | COL10A1 | ENSP00000225964 | ENSP00000243222 | collagen, type I, alpha 1 | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | 0.944 |
COL1A1 | COL1A2 | ENSP00000225964 | ENSP00000297268 | collagen, type I, alpha 1 | collagen, type I, alpha 2 | 0.963 |
COL1A1 | COL3A1 | ENSP00000225964 | ENSP00000304408 | collagen, type I, alpha 1 | collagen, type III, alpha 1 | 0.943 |
COL1A1 | CRTAP | ENSP00000225964 | ENSP00000323696 | collagen, type I, alpha 1 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | 0.749 |
COL1A1 | LEPRE1 | ENSP00000225964 | ENSP00000296388 | collagen, type I, alpha 1 | leucine proline-enriched proteoglycan (leprecan) 1 | 0.966 |
COL1A1 | LEPREL1 | ENSP00000225964 | ENSP00000316881 | collagen, type I, alpha 1 | leprecan-like 1; Shows prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types II, IV and V (By similarity) | 0.900 |
COL1A1 | P4HB | ENSP00000225964 | ENSP00000327801 | collagen, type I, alpha 1 | prolyl 4-hydroxylase, beta polypeptide; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with [...] | 0.964 |
COL1A1 | UBC | ENSP00000225964 | ENSP00000344818 | collagen, type I, alpha 1 | ubiquitin C | 0.635 |
COL1A2 | COL10A1 | ENSP00000297268 | ENSP00000243222 | collagen, type I, alpha 2 | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | 0.926 |
COL1A2 | COL1A1 | ENSP00000297268 | ENSP00000225964 | collagen, type I, alpha 2 | collagen, type I, alpha 1 | 0.963 |
COL1A2 | COL3A1 | ENSP00000297268 | ENSP00000304408 | collagen, type I, alpha 2 | collagen, type III, alpha 1 | 0.921 |
COL1A2 | CRTAP | ENSP00000297268 | ENSP00000323696 | collagen, type I, alpha 2 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | 0.759 |
COL1A2 | LEPRE1 | ENSP00000297268 | ENSP00000296388 | collagen, type I, alpha 2 | leucine proline-enriched proteoglycan (leprecan) 1 | 0.966 |
COL1A2 | LEPREL1 | ENSP00000297268 | ENSP00000316881 | collagen, type I, alpha 2 | leprecan-like 1; Shows prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types II, IV and V (By similarity) | 0.904 |