| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AZI1 | BORA | ENSP00000393583 | ENSP00000375082 | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | bora, aurora kinase A activator; Required for the activation of AURKA at the onset of mitosis | 0.900 |
| AZI1 | CEP135 | ENSP00000393583 | ENSP00000257287 | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | centrosomal protein 135kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole | 0.918 |
| AZI1 | CEP290 | ENSP00000393583 | ENSP00000448012 | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | 0.925 |
| AZI1 | CEP70 | ENSP00000393583 | ENSP00000264982 | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | centrosomal protein 70kDa | 0.967 |
| AZI1 | FGFR1OP | ENSP00000393583 | ENSP00000355812 | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | FGFR1 oncogene partner; Required for anchoring microtubules to the centrosomes | 0.900 |
| AZI1 | OFD1 | ENSP00000393583 | ENSP00000344314 | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | oral-facial-digital syndrome 1; Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis (By similarity) | 0.913 |
| AZI1 | PCNT | ENSP00000393583 | ENSP00000352572 | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | pericentrin; Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome | 0.915 |
| BORA | AZI1 | ENSP00000375082 | ENSP00000393583 | bora, aurora kinase A activator; Required for the activation of AURKA at the onset of mitosis | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | 0.900 |
| BORA | CEP135 | ENSP00000375082 | ENSP00000257287 | bora, aurora kinase A activator; Required for the activation of AURKA at the onset of mitosis | centrosomal protein 135kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole | 0.900 |
| BORA | CEP290 | ENSP00000375082 | ENSP00000448012 | bora, aurora kinase A activator; Required for the activation of AURKA at the onset of mitosis | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | 0.900 |
| BORA | CEP70 | ENSP00000375082 | ENSP00000264982 | bora, aurora kinase A activator; Required for the activation of AURKA at the onset of mitosis | centrosomal protein 70kDa | 0.900 |
| BORA | FGFR1OP | ENSP00000375082 | ENSP00000355812 | bora, aurora kinase A activator; Required for the activation of AURKA at the onset of mitosis | FGFR1 oncogene partner; Required for anchoring microtubules to the centrosomes | 0.900 |
| BORA | OFD1 | ENSP00000375082 | ENSP00000344314 | bora, aurora kinase A activator; Required for the activation of AURKA at the onset of mitosis | oral-facial-digital syndrome 1; Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis (By similarity) | 0.900 |
| BORA | PCNT | ENSP00000375082 | ENSP00000352572 | bora, aurora kinase A activator; Required for the activation of AURKA at the onset of mitosis | pericentrin; Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome | 0.905 |
| CCDC13 | CEP290 | ENSP00000309836 | ENSP00000448012 | coiled-coil domain containing 13 | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | 0.412 |
| CEP120 | CEP135 | ENSP00000303058 | ENSP00000257287 | centrosomal protein 120kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity) | centrosomal protein 135kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole | 0.665 |
| CEP120 | CEP70 | ENSP00000303058 | ENSP00000264982 | centrosomal protein 120kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity) | centrosomal protein 70kDa | 0.567 |
| CEP120 | KIAA1009 | ENSP00000303058 | ENSP00000385215 | centrosomal protein 120kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity) | KIAA1009; Functions in cell division regulating chromosome segregation and mitotic spindle assembly | 0.884 |
| CEP120 | PCNT | ENSP00000303058 | ENSP00000352572 | centrosomal protein 120kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity) | pericentrin; Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome | 0.565 |
| CEP135 | AZI1 | ENSP00000257287 | ENSP00000393583 | centrosomal protein 135kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole | 5-azacytidine induced 1; May play a role in spermatogenesis (By similarity) | 0.918 |
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