node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADRBK1 | ADRBK2 | ENSP00000312262 | ENSP00000317578 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | 0.842 |
ADRBK1 | F2R | ENSP00000312262 | ENSP00000321326 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | coagulation factor II (thrombin) receptor; High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development | 0.900 |
ADRBK1 | TBXA2R | ENSP00000312262 | ENSP00000393333 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | thromboxane A2 receptor; Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase | 0.904 |
ADRBK1 | UBC | ENSP00000312262 | ENSP00000344818 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | ubiquitin C | 0.864 |
ADRBK2 | ADRBK1 | ENSP00000317578 | ENSP00000312262 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | 0.842 |
ADRBK2 | F2R | ENSP00000317578 | ENSP00000321326 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | coagulation factor II (thrombin) receptor; High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development | 0.900 |
ADRBK2 | OR10G3 | ENSP00000317578 | ENSP00000302437 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 10, subfamily G, member 3; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR10V1 | ENSP00000317578 | ENSP00000302199 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 10, subfamily V, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR1A1 | ENSP00000317578 | ENSP00000305207 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 1, subfamily A, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR1L3 | ENSP00000317578 | ENSP00000302863 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 1, subfamily L, member 3; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR2D2 | ENSP00000317578 | ENSP00000299459 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 2, subfamily D, member 2; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR4D6 | ENSP00000317578 | ENSP00000300127 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 4, subfamily D, member 6; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR51B5 | ENSP00000317578 | ENSP00000300773 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 51, subfamily B, member 5; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR51Q1 | ENSP00000317578 | ENSP00000300778 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 51, subfamily Q, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR52K1 | ENSP00000317578 | ENSP00000302422 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 52, subfamily K, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR5A1 | ENSP00000317578 | ENSP00000303096 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 5, subfamily A, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR5A2 | ENSP00000317578 | ENSP00000303834 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 5, subfamily A, member 2; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR5AP2 | ENSP00000317578 | ENSP00000303111 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 5, subfamily AP, member 2; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR5AR1 | ENSP00000317578 | ENSP00000302639 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 5, subfamily AR, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR5AU1 | ENSP00000317578 | ENSP00000302057 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 5, subfamily AU, member 1; Odorant receptor (Potential) | 0.800 |