node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADRBK1 | ADRBK2 | ENSP00000312262 | ENSP00000317578 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | 0.842 |
ADRBK1 | F2R | ENSP00000312262 | ENSP00000321326 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | coagulation factor II (thrombin) receptor; High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development | 0.900 |
ADRBK1 | TBXA2R | ENSP00000312262 | ENSP00000393333 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | thromboxane A2 receptor; Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase | 0.904 |
ADRBK1 | UBC | ENSP00000312262 | ENSP00000344818 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | ubiquitin C | 0.864 |
ADRBK1 | XCR1 | ENSP00000312262 | ENSP00000310405 | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | chemokine (C motif) receptor 1; Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level | 0.900 |
ADRBK2 | ADRBK1 | ENSP00000317578 | ENSP00000312262 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner | 0.842 |
ADRBK2 | F2R | ENSP00000317578 | ENSP00000321326 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | coagulation factor II (thrombin) receptor; High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development | 0.900 |
ADRBK2 | OR10Q1 | ENSP00000317578 | ENSP00000314324 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 10, subfamily Q, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR1F1 | ENSP00000317578 | ENSP00000305424 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 1, subfamily F, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR2A1 | ENSP00000317578 | ENSP00000386175 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 2, subfamily A, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR2C1 | ENSP00000317578 | ENSP00000307726 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 2, subfamily C, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR2S2 | ENSP00000317578 | ENSP00000344040 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 2, subfamily S, member 2; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR2T2 | ENSP00000317578 | ENSP00000343062 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 2, subfamily T, member 2; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR4M1 | ENSP00000317578 | ENSP00000319654 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 4, subfamily M, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR51M1 | ENSP00000317578 | ENSP00000333196 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 51, subfamily M, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR52K1 | ENSP00000317578 | ENSP00000302422 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 52, subfamily K, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR52N2 | ENSP00000317578 | ENSP00000322801 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 52, subfamily N, member 2; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR5AN1 | ENSP00000317578 | ENSP00000320302 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 5, subfamily AN, member 1; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR5AP2 | ENSP00000317578 | ENSP00000303111 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 5, subfamily AP, member 2; Odorant receptor (Potential) | 0.800 |
ADRBK2 | OR5B17 | ENSP00000317578 | ENSP00000349945 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | olfactory receptor, family 5, subfamily B, member 17; Odorant receptor (Potential) | 0.800 |