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PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta); Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane (728 aa) | |||
ABI3 | ABI family, member 3; May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility (366 aa) | |||
BYSL | bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos (437 aa) | |||
CENPK | centromere protein K; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore (269 aa) | |||
CDK2AP1 | cyclin-dependent kinase 2 associated protein 1; specific inhibitor of the cell-cycle kinase CDK2 (By similarity) (115 aa) | |||
CSPP1 | centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization (1221 aa) | |||
EIF2B2 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP (351 aa) | |||
RDM1 | RAD52 motif 1 (284 aa) | |||
CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 (126 aa) | |||
PRKCDBP | protein kinase C, delta binding protein; Seems to have an immune potentiation function (By similarity) (261 aa) | |||
MRFAP1L1 | Morf4 family associated protein 1-like 1 (127 aa) | |||
MRFAP1 | Morf4 family associated protein 1 (127 aa) | |||
MORF4L1 | mortality factor 4 like 1 (362 aa) | |||
C3orf62 | chromosome 3 open reading frame 62 (267 aa) | |||
UBC | ubiquitin C (685 aa) | |||
HTT | huntingtin; May play a role in microtubule-mediated transport or vesicle function (3142 aa) | |||
TMEM126B | transmembrane protein 126B; Involved in assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) (By similarity) (230 aa) | |||
TSNAX | translin-associated factor X; Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (290 aa) | |||
SFR1 | SWI5-dependent recombination repair 1; Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination (245 aa) | |||
UBTD1 | ubiquitin domain containing 1 (227 aa) | |||
ABI1 | abl-interactor 1 (508 aa) | |||
SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) (513 aa) | |||
ZDHHC17 | zinc finger, DHHC-type containing 17; Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. Palmitoylates MPP1 in erythrocytes. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. Has transforming activity. Mediates Mg(2+) transport (632 aa) | |||
PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells (By similarity) (269 aa) | |||
CAGE1 | cancer antigen 1 (839 aa) | |||
NU | proteasome subunit alpha type-1 isoform 3 ; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity) (164 aa) |