22 items (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Predicted Interactions

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Your Input:
	TRIM23	tripartite motif containing 23; Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in ’Lys-63’-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit (574 aa)
	UMPS	uridine monophosphate synthetase (480 aa)
	METTL25	methyltransferase like 25; Putative methyltransferase (By similarity) (603 aa)
	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1; Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (1280 aa)
	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization (895 aa)
	PFAS	phosphoribosylformylglycinamidine synthase (1338 aa)
	SLC38A9	solute carrier family 38, member 9; Putative sodium-dependent amino acid/proton antiporter (By similarity) (561 aa)
	HTR3C	5-hydroxytryptamine (serotonin) receptor 3C, ionotropic; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel (447 aa)
	TMEM186	transmembrane protein 186 (213 aa)
	ABCC5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (1437 aa)
	TMEM104	transmembrane protein 104 (496 aa)
	WLS	wntless homolog (Drosophila); Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity) (543 aa)
	HTR3A	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel (516 aa)
	ABCB8	ATP-binding cassette, sub-family B (MDR/TAP), member 8 (718 aa)
	FAM69B	family with sequence similarity 69, member B (431 aa)
	ABCC10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10; ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion (1492 aa)
	BICC1	bicaudal C homolog 1 (Drosophila); Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development (974 aa)
	SLC38A10	solute carrier family 38, member 10; Putative sodium-dependent amino acid/proton antiporter (By similarity) (1119 aa)
	B4GALT1	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (398 aa)
	RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis); Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected (318 aa)
	RIMS2	regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein (1349 aa)
	SEC11C	SEC11 homolog C (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) (192 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB1	UMPS	ENSP00000265724	ENSP00000232607	ATP-binding cassette, sub-family B (MDR/TAP), member 1; Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells	uridine monophosphate synthetase	0.439
ABCC10	TMEM104	ENSP00000361608	ENSP00000334849	ATP-binding cassette, sub-family C (CFTR/MRP), member 10; ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion	transmembrane protein 104	0.593
HTR3A	HTR3C	ENSP00000347754	ENSP00000322617	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel	5-hydroxytryptamine (serotonin) receptor 3C, ionotropic; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel	0.911
HTR3C	HTR3A	ENSP00000322617	ENSP00000347754	5-hydroxytryptamine (serotonin) receptor 3C, ionotropic; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel	0.911
PFAS	UMPS	ENSP00000313490	ENSP00000232607	phosphoribosylformylglycinamidine synthase	uridine monophosphate synthetase	0.758
SEC11C	UMPS	ENSP00000468633	ENSP00000232607	SEC11 homolog C (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	uridine monophosphate synthetase	0.419
TMEM104	ABCC10	ENSP00000334849	ENSP00000361608	transmembrane protein 104	ATP-binding cassette, sub-family C (CFTR/MRP), member 10; ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion	0.593
UMPS	ABCB1	ENSP00000232607	ENSP00000265724	uridine monophosphate synthetase	ATP-binding cassette, sub-family B (MDR/TAP), member 1; Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells	0.439
UMPS	PFAS	ENSP00000232607	ENSP00000313490	uridine monophosphate synthetase	phosphoribosylformylglycinamidine synthase	0.758
UMPS	SEC11C	ENSP00000232607	ENSP00000468633	uridine monophosphate synthetase	SEC11 homolog C (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	0.419

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