11 items (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Your Input:
	MFAP1	microfibrillar-associated protein 1; Component of the elastin-associated microfibrils (439 aa)
	EFEMP2	EGF containing fibulin-like extracellular matrix protein 2 (443 aa)
	MFAP3	microfibrillar-associated protein 3; Component of the elastin-associated microfibrils (362 aa)
	FBLN1	fibulin 1 (703 aa)
	UBC	ubiquitin C (685 aa)
	FBLN5	fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling (448 aa)
	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth (493 aa)
	MFAP5	microfibrillar associated protein 5; Component of the elastin-associated microfibrils (173 aa)
	MFAP2	microfibrillar-associated protein 2; Component of the elastin-associated microfibrils (183 aa)
	MFAP4	microfibrillar-associated protein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions (279 aa)
	FBLN2	fibulin 2; Its binding to fibronectin and some other ligands is calcium dependent (1231 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFEMP1	EFEMP2	ENSP00000347596	ENSP00000309953	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	EGF containing fibulin-like extracellular matrix protein 2	0.902
EFEMP1	FBLN1	ENSP00000347596	ENSP00000331544	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	fibulin 1	0.914
EFEMP1	FBLN2	ENSP00000347596	ENSP00000384169	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	fibulin 2; Its binding to fibronectin and some other ligands is calcium dependent	0.910
EFEMP1	FBLN5	ENSP00000347596	ENSP00000345008	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling	0.904
EFEMP1	MFAP1	ENSP00000347596	ENSP00000267812	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	microfibrillar-associated protein 1; Component of the elastin-associated microfibrils	0.921
EFEMP1	MFAP2	ENSP00000347596	ENSP00000364685	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	microfibrillar-associated protein 2; Component of the elastin-associated microfibrils	0.927
EFEMP1	MFAP3	ENSP00000347596	ENSP00000322956	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	microfibrillar-associated protein 3; Component of the elastin-associated microfibrils	0.900
EFEMP1	MFAP4	ENSP00000347596	ENSP00000378957	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	microfibrillar-associated protein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions	0.905
EFEMP1	MFAP5	ENSP00000347596	ENSP00000352455	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	microfibrillar associated protein 5; Component of the elastin-associated microfibrils	0.922
EFEMP2	EFEMP1	ENSP00000309953	ENSP00000347596	EGF containing fibulin-like extracellular matrix protein 2	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	0.902
EFEMP2	FBLN1	ENSP00000309953	ENSP00000331544	EGF containing fibulin-like extracellular matrix protein 2	fibulin 1	0.911
EFEMP2	FBLN2	ENSP00000309953	ENSP00000384169	EGF containing fibulin-like extracellular matrix protein 2	fibulin 2; Its binding to fibronectin and some other ligands is calcium dependent	0.909
EFEMP2	FBLN5	ENSP00000309953	ENSP00000345008	EGF containing fibulin-like extracellular matrix protein 2	fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling	0.957
EFEMP2	MFAP1	ENSP00000309953	ENSP00000267812	EGF containing fibulin-like extracellular matrix protein 2	microfibrillar-associated protein 1; Component of the elastin-associated microfibrils	0.920
EFEMP2	MFAP2	ENSP00000309953	ENSP00000364685	EGF containing fibulin-like extracellular matrix protein 2	microfibrillar-associated protein 2; Component of the elastin-associated microfibrils	0.936
EFEMP2	MFAP3	ENSP00000309953	ENSP00000322956	EGF containing fibulin-like extracellular matrix protein 2	microfibrillar-associated protein 3; Component of the elastin-associated microfibrils	0.900
EFEMP2	MFAP4	ENSP00000309953	ENSP00000378957	EGF containing fibulin-like extracellular matrix protein 2	microfibrillar-associated protein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions	0.905
EFEMP2	MFAP5	ENSP00000309953	ENSP00000352455	EGF containing fibulin-like extracellular matrix protein 2	microfibrillar associated protein 5; Component of the elastin-associated microfibrils	0.931
FBLN1	EFEMP1	ENSP00000331544	ENSP00000347596	fibulin 1	EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth	0.914
FBLN1	EFEMP2	ENSP00000331544	ENSP00000309953	fibulin 1	EGF containing fibulin-like extracellular matrix protein 2	0.911

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