node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTR2 | TOM1L1 | ENSP00000367220 | ENSP00000460823 | ARP2 actin-related protein 2 homolog (yeast); Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | target of myb1 (chicken)-like 1; Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity) | 0.498 |
ACTR2 | UBC | ENSP00000367220 | ENSP00000344818 | ARP2 actin-related protein 2 homolog (yeast); Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament | ubiquitin C | 0.995 |
ARMC9 | CRTAP | ENSP00000258417 | ENSP00000323696 | armadillo repeat containing 9 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | 0.408 |
ARMC9 | UBC | ENSP00000258417 | ENSP00000344818 | armadillo repeat containing 9 | ubiquitin C | 0.483 |
CRTAP | ARMC9 | ENSP00000323696 | ENSP00000258417 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | armadillo repeat containing 9 | 0.408 |
CRTAP | GPN1 | ENSP00000323696 | ENSP00000264718 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | GPN-loop GTPase 1; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA | 0.416 |
CRTAP | LEPRE1 | ENSP00000323696 | ENSP00000296388 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | leucine proline-enriched proteoglycan (leprecan) 1 | 0.950 |
CRTAP | PPIB | ENSP00000323696 | ENSP00000300026 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | peptidylprolyl isomerase B (cyclophilin B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides | 0.998 |
CRTAP | SERPINH1 | ENSP00000323696 | ENSP00000350894 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen | 0.951 |
CRTAP | SH3GL1 | ENSP00000323696 | ENSP00000269886 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | 0.426 |
CRTAP | SH3GLB2 | ENSP00000323696 | ENSP00000361640 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | SH3-domain GRB2-like endophilin B2 | 0.416 |
CRTAP | SP100 | ENSP00000323696 | ENSP00000343023 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | SP100 nuclear antigen | 0.518 |
CRTAP | SURF2 | ENSP00000323696 | ENSP00000361032 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | surfeit 2 | 0.465 |
CRTAP | TOM1L1 | ENSP00000323696 | ENSP00000460823 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | target of myb1 (chicken)-like 1; Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity) | 0.424 |
CRTAP | UBC | ENSP00000323696 | ENSP00000344818 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | ubiquitin C | 0.802 |
CRTAP | WDR48 | ENSP00000323696 | ENSP00000307491 | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | WD repeat domain 48 | 0.487 |
GPN1 | CRTAP | ENSP00000264718 | ENSP00000323696 | GPN-loop GTPase 1; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues | 0.416 |
GPN1 | LEPRE1 | ENSP00000264718 | ENSP00000296388 | GPN-loop GTPase 1; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA | leucine proline-enriched proteoglycan (leprecan) 1 | 0.468 |
GPN1 | SURF2 | ENSP00000264718 | ENSP00000361032 | GPN-loop GTPase 1; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA | surfeit 2 | 0.476 |
GPN1 | UBC | ENSP00000264718 | ENSP00000344818 | GPN-loop GTPase 1; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA | ubiquitin C | 0.937 |