Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
MYRIP MYRIP EXOC3L2 EXOC3L2 TNFAIP2 TNFAIP2 EXOC6B EXOC6B EXOC8 EXOC8 EXOC3L1 EXOC3L1 EXOC6 EXOC6 EXOC4 EXOC4 EXOC3 EXOC3 EXOC1 EXOC1 EXOC2 EXOC2 EXOC3L4 EXOC3L4 EXOC7 EXOC7 SEPT2 SEPT2 SNAP25 SNAP25 STX1A STX1A STX4 STX4 STXBP6 STXBP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
STX1Asyntaxin 1A (brain) (288 aa)
EXOC2exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (924 aa)
EXOC3L2exocyst complex component 3-like 2 (409 aa)
EXOC4exocyst complex component 4; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (By similarity) (974 aa)
SNAP25synaptosomal-associated protein, 25kDa (206 aa)
EXOC6exocyst complex component 6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity) (804 aa)
EXOC6Bexocyst complex component 6B; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (811 aa)
MYRIPmyosin VIIA and Rab interacting protein (859 aa)
STX4syntaxin 4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones (297 aa)
EXOC3exocyst complex component 3; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (745 aa)
STXBP6syntaxin binding protein 6 (amisyn); Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis (210 aa)
EXOC3L1exocyst complex component 3-like 1; As part of the exocyst, may play a role in regulated exocytosis of insulin granules (By similarity) (746 aa)
EXOC1exocyst complex component 1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (894 aa)
TNFAIP2tumor necrosis factor, alpha-induced protein 2; May play a role as a mediator of inflammation and angiogenesis (654 aa)
EXOC7exocyst complex component 7 (735 aa)
SEPT2septin 2; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongat [...] (361 aa)
EXOC8exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (725 aa)
EXOC3L4exocyst complex component 3-like 4 (722 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (33%)