Your Input:
|
||||
MED31 | mediator complex subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (131 aa) | |||
LMAN1 | lectin, mannose-binding, 1 (510 aa) | |||
TYRO3 | TYRO3 protein tyrosine kinase; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, [...] (890 aa) | |||
KLK4 | kallikrein-related peptidase 4; Involved in enamel formation (254 aa) | |||
PLAUR | plasminogen activator, urokinase receptor (335 aa) | |||
NGF | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival (241 aa) | |||
SHBG | sex hormone-binding globulin (402 aa) | |||
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (423 aa) | |||
SLC4A4 | solute carrier family 4, sodium bicarbonate cotransporter, member 4 (1094 aa) |