Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
WBSCR16 WBSCR16 DHRS4 DHRS4 NDUFAF3 NDUFAF3 NDUFAF5 NDUFAF5 PHYHIPL PHYHIPL RBP1 RBP1 MRPL13 MRPL13 GLRX5 GLRX5 BOLA1 BOLA1 NDUFS2 NDUFS2 NDUFS3 NDUFS3 PMPCA PMPCA NDUFA5 NDUFA5 PMPCB PMPCB RBP5 RBP5 ECH1 ECH1 RBP2 RBP2 ATP5E ATP5E PITRM1 PITRM1 ABHD11 ABHD11 NRD1 NRD1 BCKDHA BCKDHA CLPB CLPB TMC1 TMC1 CHCHD2 CHCHD2 C17orf89 C17orf89
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
ECH1enoyl CoA hydratase 1, peroxisomal; Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA (By similarity) (328 aa)
ABHD11abhydrolase domain containing 11 (315 aa)
RBP2retinol binding protein 2, cellular; Intracellular transport of retinol (134 aa)
RBP1retinol binding protein 1, cellular; Intracellular transport of retinol (197 aa)
ATP5EATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled [...] (51 aa)
PMPCBpeptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) (489 aa)
NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (264 aa)
RBP5retinol binding protein 5, cellular; Intracellular transport of retinol (135 aa)
BCKDHAbranched chain keto acid dehydrogenase E1, alpha polypeptide; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components- branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (445 aa)
CLPBClpB caseinolytic peptidase B homolog (E. coli); May function as a regulatory ATPase and be related to secretion/protein trafficking process (707 aa)
TMC1transmembrane channel-like 1; Probable ion channel required for the normal function of cochlear hair cells (By similarity) (760 aa)
MRPL13mitochondrial ribosomal protein L13 (178 aa)
NDUFAF3NADH dehydrogenase (ubiquinone) complex I, assembly factor 3; Essential factor for the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) (184 aa)
DHRS4dehydrogenase/reductase (SDR family) member 4 (278 aa)
GLRX5glutaredoxin 5; Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (157 aa)
WBSCR16Williams-Beuren syndrome chromosome region 16 (464 aa)
NRD1nardilysin (N-arginine dibasic convertase); Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs (1219 aa)
NDUFA5NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (116 aa)
NDUFS2NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase); Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (463 aa)
BOLA1bolA homolog 1 (E. coli) (137 aa)
PMPCApeptidase (mitochondrial processing) alpha; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) (525 aa)
PHYHIPLphytanoyl-CoA 2-hydroxylase interacting protein-like; May play a role in the development of the central system (By similarity) (376 aa)
NDUFAF5NADH dehydrogenase (ubiquinone) complex I, assembly factor 5; Involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. May have methyltransferase activity (345 aa)
PITRM1pitrilysin metallopeptidase 1 (1038 aa)
CHCHD2coiled-coil-helix-coiled-coil-helix domain containing 2 (151 aa)
C17orf89chromosome 17 open reading frame 89 (74 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (47%)