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TIMP1 | TIMP metallopeptidase inhibitor 1; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14 (207 aa) | |||
TUSC3 | tumor suppressor candidate 3; Magnesium transporter. May be involved in N- glycosylation through its association with N-oligosaccharyl transferase (348 aa) | |||
CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae); Involved in lipid remodeling during GPI-anchor maturation (By similarity) (699 aa) | |||
FBXL4 | F-box and leucine-rich repeat protein 4 (621 aa) | |||
MOGS | mannosyl-oligosaccharide glucosidase; Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner (837 aa) | |||
SI | sucrase-isomaltase (alpha-glucosidase); Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides (1827 aa) | |||
CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2225 aa) | |||
ADAM2 | ADAM metallopeptidase domain 2; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (735 aa) | |||
PGAP2 | post-GPI attachment to proteins 2; Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity) (315 aa) | |||
KIAA1161 | KIAA1161; Putative glucosidase (By similarity) (680 aa) | |||
RER1 | RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae); Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment (By similarity) (196 aa) | |||
PCSK9 | proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members- low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (692 aa) | |||
GAA | glucosidase, alpha; acid; Essential for the degradation of glygogen to glucose in lysosomes (952 aa) | |||
DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2; Co-chaperone of Hsc70 (412 aa) | |||
HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER (654 aa) | |||
GANC | glucosidase, alpha; neutral C; Has alpha-glucosidase activity (914 aa) | |||
CLGN | calmegin; Probably plays an important role in spermatogenesis. Binds calcium ions (610 aa) | |||
GANAB | glucosidase, alpha; neutral AB; Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (966 aa) | |||
TLR9 | toll-like receptor 9 (1032 aa) | |||
MAGT1 | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells (367 aa) | |||
DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1; Co-chaperone of Hsc70. Seems to play a role in protein import into mitochondria (397 aa) | |||
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 (426 aa) | |||
PIGG | phosphatidylinositol glycan anchor biosynthesis, class G (983 aa) | |||
CD289 | TLR9 (1186 aa) | |||
ENSG00000257743 | Putative maltase-glucoamylase-like protein FLJ16351 (2259 aa) | |||
MGAM | maltase-glucoamylase (alpha-glucosidase); May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing (1857 aa) |