node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APP | UBC | ENSP00000284981 | ENSP00000344818 | amyloid beta (A4) precursor protein | ubiquitin C | 0.991 |
MAX | MINA | ENSP00000351490 | ENSP00000328251 | MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5’-CAC[GA]TG-3’. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 ’Lys-9’ histone methyltransferase activity | MYC induced nuclear antigen | 0.900 |
MAX | MYC | ENSP00000351490 | ENSP00000367207 | MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5’-CAC[GA]TG-3’. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 ’Lys-9’ histone methyltransferase activity | v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes | 0.999 |
MINA | MAX | ENSP00000328251 | ENSP00000351490 | MYC induced nuclear antigen | MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5’-CAC[GA]TG-3’. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 ’Lys-9’ histone methyltransferase activity | 0.900 |
MINA | MYBBP1A | ENSP00000328251 | ENSP00000370968 | MYC induced nuclear antigen | MYB binding protein (P160) 1a; May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity) | 0.625 |
MINA | MYC | ENSP00000328251 | ENSP00000367207 | MYC induced nuclear antigen | v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes | 0.992 |
MINA | NAA16 | ENSP00000328251 | ENSP00000368716 | MYC induced nuclear antigen | N(alpha)-acetyltransferase 16, NatA auxiliary subunit; May belong to a complex displaying N-terminal acetyltransferase activity (By similarity) | 0.671 |
MINA | RPL27A | ENSP00000328251 | ENSP00000346015 | MYC induced nuclear antigen | ribosomal protein L27a | 0.598 |
MINA | SP7 | ENSP00000328251 | ENSP00000302812 | MYC induced nuclear antigen | Sp7 transcription factor; Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity) | 0.636 |
MINA | SP8 | ENSP00000328251 | ENSP00000408792 | MYC induced nuclear antigen | Sp8 transcription factor; Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity) | 0.644 |
MINA | SP9 | ENSP00000328251 | ENSP00000378418 | MYC induced nuclear antigen | Sp9 transcription factor homolog (mouse); Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity) | 0.624 |
MINA | TXNL1 | ENSP00000328251 | ENSP00000217515 | MYC induced nuclear antigen | thioredoxin-like 1; Active thioredoxin with a redox potential of about -250 mV | 0.644 |
MINA | UBC | ENSP00000328251 | ENSP00000344818 | MYC induced nuclear antigen | ubiquitin C | 0.799 |
MYBBP1A | MINA | ENSP00000370968 | ENSP00000328251 | MYB binding protein (P160) 1a; May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity) | MYC induced nuclear antigen | 0.625 |
MYBBP1A | UBC | ENSP00000370968 | ENSP00000344818 | MYB binding protein (P160) 1a; May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity) | ubiquitin C | 0.958 |
MYC | MAX | ENSP00000367207 | ENSP00000351490 | v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes | MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5’-CAC[GA]TG-3’. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 ’Lys-9’ histone methyltransferase activity | 0.999 |
MYC | MINA | ENSP00000367207 | ENSP00000328251 | v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes | MYC induced nuclear antigen | 0.992 |
MYC | UBC | ENSP00000367207 | ENSP00000344818 | v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes | ubiquitin C | 0.999 |
NAA16 | MINA | ENSP00000368716 | ENSP00000328251 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit; May belong to a complex displaying N-terminal acetyltransferase activity (By similarity) | MYC induced nuclear antigen | 0.671 |
NAA16 | UBC | ENSP00000368716 | ENSP00000344818 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit; May belong to a complex displaying N-terminal acetyltransferase activity (By similarity) | ubiquitin C | 0.796 |