| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DBX2 | ISL1 | ENSP00000331470 | ENSP00000230658 | developing brain homeobox 2 | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | 0.543 |
| DBX2 | ISL2 | ENSP00000331470 | ENSP00000290759 | developing brain homeobox 2 | ISL LIM homeobox 2; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways (By similarity) | 0.450 |
| DBX2 | LHX1 | ENSP00000331470 | ENSP00000254457 | developing brain homeobox 2 | LIM homeobox 1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis | 0.428 |
| ISL1 | DBX2 | ENSP00000230658 | ENSP00000331470 | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | developing brain homeobox 2 | 0.543 |
| ISL1 | ISL2 | ENSP00000230658 | ENSP00000290759 | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | ISL LIM homeobox 2; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways (By similarity) | 0.577 |
| ISL1 | LHX1 | ENSP00000230658 | ENSP00000254457 | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | LIM homeobox 1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis | 0.635 |
| ISL1 | LMX1A | ENSP00000230658 | ENSP00000294816 | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | LIM homeobox transcription factor 1, alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity) | 0.615 |
| ISL1 | WNT1 | ENSP00000230658 | ENSP00000293549 | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | wingless-type MMTV integration site family, member 1; Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters | 0.558 |
| ISL1 | WNT3A | ENSP00000230658 | ENSP00000284523 | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | wingless-type MMTV integration site family, member 3A; Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube | 0.557 |
| ISL2 | DBX2 | ENSP00000290759 | ENSP00000331470 | ISL LIM homeobox 2; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways (By similarity) | developing brain homeobox 2 | 0.450 |
| ISL2 | ISL1 | ENSP00000290759 | ENSP00000230658 | ISL LIM homeobox 2; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways (By similarity) | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | 0.577 |
| LHX1 | DBX2 | ENSP00000254457 | ENSP00000331470 | LIM homeobox 1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis | developing brain homeobox 2 | 0.428 |
| LHX1 | ISL1 | ENSP00000254457 | ENSP00000230658 | LIM homeobox 1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | 0.635 |
| LHX2 | WNT1 | ENSP00000362717 | ENSP00000293549 | LIM homeobox 2; Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity) | wingless-type MMTV integration site family, member 1; Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters | 0.552 |
| LHX2 | WNT3A | ENSP00000362717 | ENSP00000284523 | LIM homeobox 2; Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity) | wingless-type MMTV integration site family, member 3A; Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube | 0.669 |
| LHX9 | WNT1 | ENSP00000356357 | ENSP00000293549 | LIM homeobox 9; Involved in gonadal development (By similarity) | wingless-type MMTV integration site family, member 1; Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters | 0.522 |
| LHX9 | WNT3A | ENSP00000356357 | ENSP00000284523 | LIM homeobox 9; Involved in gonadal development (By similarity) | wingless-type MMTV integration site family, member 3A; Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube | 0.544 |
| LMX1A | ISL1 | ENSP00000294816 | ENSP00000230658 | LIM homeobox transcription factor 1, alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity) | ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) | 0.615 |
| LMX1A | WNT1 | ENSP00000294816 | ENSP00000293549 | LIM homeobox transcription factor 1, alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity) | wingless-type MMTV integration site family, member 1; Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters | 0.910 |
| LMX1A | WNT3A | ENSP00000294816 | ENSP00000284523 | LIM homeobox transcription factor 1, alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity) | wingless-type MMTV integration site family, member 3A; Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube | 0.526 |
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