| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATXN1 | UBC | ENSP00000244769 | ENSP00000344818 | ataxin 1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function | ubiquitin C | 0.596 |
| ATXN1 | UBQLN4 | ENSP00000244769 | ENSP00000357292 | ataxin 1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function | ubiquilin 4; Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation | 0.969 |
| CTBP1 | CTBP2 | ENSP00000290921 | ENSP00000311825 | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | 0.921 |
| CTBP1 | UBC | ENSP00000290921 | ENSP00000344818 | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | ubiquitin C | 0.981 |
| CTBP2 | CTBP1 | ENSP00000311825 | ENSP00000290921 | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | 0.921 |
| CTBP2 | RAI2 | ENSP00000311825 | ENSP00000333456 | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | retinoic acid induced 2 | 0.555 |
| CTBP2 | UBC | ENSP00000311825 | ENSP00000344818 | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | ubiquitin C | 0.980 |
| FHL2 | UBC | ENSP00000322909 | ENSP00000344818 | four and a half LIM domains 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation | ubiquitin C | 0.800 |
| RAI2 | CTBP2 | ENSP00000333456 | ENSP00000311825 | retinoic acid induced 2 | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | 0.555 |
| RAI2 | SGTB | ENSP00000333456 | ENSP00000370395 | retinoic acid induced 2 | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity) | 0.717 |
| SGTB | RAI2 | ENSP00000370395 | ENSP00000333456 | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity) | retinoic acid induced 2 | 0.717 |
| SGTB | UBC | ENSP00000370395 | ENSP00000344818 | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity) | ubiquitin C | 0.766 |
| UBC | ATXN1 | ENSP00000344818 | ENSP00000244769 | ubiquitin C | ataxin 1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function | 0.596 |
| UBC | CTBP1 | ENSP00000344818 | ENSP00000290921 | ubiquitin C | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | 0.981 |
| UBC | CTBP2 | ENSP00000344818 | ENSP00000311825 | ubiquitin C | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | 0.980 |
| UBC | FHL2 | ENSP00000344818 | ENSP00000322909 | ubiquitin C | four and a half LIM domains 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation | 0.800 |
| UBC | SGTB | ENSP00000344818 | ENSP00000370395 | ubiquitin C | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity) | 0.766 |
| UBC | UBQLN4 | ENSP00000344818 | ENSP00000357292 | ubiquitin C | ubiquilin 4; Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation | 0.991 |
| UBQLN4 | ATXN1 | ENSP00000357292 | ENSP00000244769 | ubiquilin 4; Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation | ataxin 1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function | 0.969 |
| UBQLN4 | UBC | ENSP00000357292 | ENSP00000344818 | ubiquilin 4; Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation | ubiquitin C | 0.991 |
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