| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADCY3 | ADCY7 | ENSP00000260600 | ENSP00000254235 | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | 0.911 |
| ADCY3 | ADCY8 | ENSP00000260600 | ENSP00000286355 | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | 0.909 |
| ADCY3 | GNAL | ENSP00000260600 | ENSP00000334051 | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | 0.931 |
| ADCY3 | UBC | ENSP00000260600 | ENSP00000344818 | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | ubiquitin C | 0.809 |
| ADCY7 | ADCY3 | ENSP00000254235 | ENSP00000260600 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | 0.911 |
| ADCY7 | ADCY8 | ENSP00000254235 | ENSP00000286355 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | 0.919 |
| ADCY7 | GNAL | ENSP00000254235 | ENSP00000334051 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | 0.916 |
| ADCY7 | UBC | ENSP00000254235 | ENSP00000344818 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | ubiquitin C | 0.740 |
| ADCY8 | ADCY3 | ENSP00000286355 | ENSP00000260600 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | 0.909 |
| ADCY8 | ADCY7 | ENSP00000286355 | ENSP00000254235 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | 0.919 |
| ADCY8 | GNAL | ENSP00000286355 | ENSP00000334051 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | 0.934 |
| ESR1 | GNAL | ENSP00000206249 | ENSP00000334051 | estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA- binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial [...] | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | 0.906 |
| ESR1 | UBC | ENSP00000206249 | ENSP00000344818 | estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA- binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial [...] | ubiquitin C | 0.999 |
| GNAL | ADCY3 | ENSP00000334051 | ENSP00000260600 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | 0.931 |
| GNAL | ADCY7 | ENSP00000334051 | ENSP00000254235 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | 0.916 |
| GNAL | ADCY8 | ENSP00000334051 | ENSP00000286355 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | 0.934 |
| GNAL | ESR1 | ENSP00000334051 | ENSP00000206249 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA- binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial [...] | 0.906 |
| GNAL | OR10K1 | ENSP00000334051 | ENSP00000289451 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | olfactory receptor, family 10, subfamily K, member 1; Odorant receptor (Potential) | 0.900 |
| GNAL | OR11H1 | ENSP00000334051 | ENSP00000252835 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | olfactory receptor, family 11, subfamily H, member 1; Odorant receptor (Potential) | 0.900 |
| GNAL | OR13C4 | ENSP00000334051 | ENSP00000277216 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters | olfactory receptor, family 13, subfamily C, member 4; Odorant receptor (Potential) | 0.900 |
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