7 items (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Your Input:
	GGNBP2	gametogenetin binding protein 2; May be involved in spermatogenesis (697 aa)
	GGN	gametogenetin; May be involved in spermatogenesis (By similarity) (652 aa)
	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis (277 aa)
	GGNBP1	gametogenetin binding protein 1 (pseudogene); May be involved in spermatogenesis (By similarity) (109 aa)
	FANCL	Fanconi anemia, complementation group L; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth (380 aa)
	OAZ3	ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells (203 aa)
	BRCA1	breast cancer 1, early onset; E3 ubiquitin-protein ligase that specifically mediates the formation of ’Lys-6’-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Reg [...] (1884 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA1	FANCL	ENSP00000418960	ENSP00000385021	breast cancer 1, early onset; E3 ubiquitin-protein ligase that specifically mediates the formation of ’Lys-6’-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Reg [...]	Fanconi anemia, complementation group L; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth	0.955
FANCL	BRCA1	ENSP00000385021	ENSP00000418960	Fanconi anemia, complementation group L; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth	breast cancer 1, early onset; E3 ubiquitin-protein ligase that specifically mediates the formation of ’Lys-6’-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Reg [...]	0.955
FANCL	GGN	ENSP00000385021	ENSP00000334940	Fanconi anemia, complementation group L; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth	gametogenetin; May be involved in spermatogenesis (By similarity)	0.752
GGN	FANCL	ENSP00000334940	ENSP00000385021	gametogenetin; May be involved in spermatogenesis (By similarity)	Fanconi anemia, complementation group L; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth	0.752
GGN	GGNBP1	ENSP00000334940	ENSP00000363582	gametogenetin; May be involved in spermatogenesis (By similarity)	gametogenetin binding protein 1 (pseudogene); May be involved in spermatogenesis (By similarity)	0.783
GGN	GGNBP2	ENSP00000334940	ENSP00000307617	gametogenetin; May be involved in spermatogenesis (By similarity)	gametogenetin binding protein 2; May be involved in spermatogenesis	0.737
GGN	OAZ3	ENSP00000334940	ENSP00000415904	gametogenetin; May be involved in spermatogenesis (By similarity)	ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells	0.766
GGNBP1	GGN	ENSP00000363582	ENSP00000334940	gametogenetin binding protein 1 (pseudogene); May be involved in spermatogenesis (By similarity)	gametogenetin; May be involved in spermatogenesis (By similarity)	0.783
GGNBP1	GGNBP2	ENSP00000363582	ENSP00000307617	gametogenetin binding protein 1 (pseudogene); May be involved in spermatogenesis (By similarity)	gametogenetin binding protein 2; May be involved in spermatogenesis	0.407
GGNBP1	OAZ3	ENSP00000363582	ENSP00000415904	gametogenetin binding protein 1 (pseudogene); May be involved in spermatogenesis (By similarity)	ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells	0.459
GGNBP2	GGN	ENSP00000307617	ENSP00000334940	gametogenetin binding protein 2; May be involved in spermatogenesis	gametogenetin; May be involved in spermatogenesis (By similarity)	0.737
GGNBP2	GGNBP1	ENSP00000307617	ENSP00000363582	gametogenetin binding protein 2; May be involved in spermatogenesis	gametogenetin binding protein 1 (pseudogene); May be involved in spermatogenesis (By similarity)	0.407
GGNBP2	OAZ3	ENSP00000307617	ENSP00000415904	gametogenetin binding protein 2; May be involved in spermatogenesis	ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells	0.747
OAZ3	GGN	ENSP00000415904	ENSP00000334940	ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells	gametogenetin; May be involved in spermatogenesis (By similarity)	0.766
OAZ3	GGNBP1	ENSP00000415904	ENSP00000363582	ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells	gametogenetin binding protein 1 (pseudogene); May be involved in spermatogenesis (By similarity)	0.459
OAZ3	GGNBP2	ENSP00000415904	ENSP00000307617	ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells	gametogenetin binding protein 2; May be involved in spermatogenesis	0.747

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