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SPATA20 | spermatogenesis associated 20; May play a role in fertility regulation (By similarity) (802 aa) | |||
ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4; It may catalyze the formation of the NeuAc-alpha-2,3- Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant. Also acts on the corresponding 1,3- galactosyl derivative (329 aa) | |||
ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (444 aa) | |||
MUC7 | mucin 7, secreted; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili (377 aa) | |||
MUC17 | mucin 17, cell surface associated; Probably plays a role in maintaining homeostasis on mucosal surfaces (4493 aa) | |||
MUCL1 | mucin-like 1; May play a role as marker for the diagnosis of metastatic breast cancer (90 aa) | |||
MUC13 | mucin 13, cell surface associated; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling (511 aa) | |||
ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1; It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O- linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values (340 aa) | |||
ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively (376 aa) | |||
MUC3A | mucin 3A, cell surface associated; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) (876 aa) | |||
ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. Prefers glycoproteins to glycolipids (By similarity) (302 aa) | |||
ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2; It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values (350 aa) | |||
MUC1 | mucin 1, cell surface associated (475 aa) | |||
BAG3 | BCL2-associated athanogene 3; Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity (575 aa) | |||
SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function (337 aa) | |||
MUC21 | mucin 21, cell surface associated (566 aa) | |||
MUC16 | mucin 16, cell surface associated; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) (14507 aa) | |||
MUC19 | mucin 19, oligomeric; May function in ocular mucus homeostasis (1640 aa) | |||
MUC20 | mucin 20, cell surface associated; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (723 aa) | |||
MUC6 | mucin 6, oligomeric mucus/gel-forming; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis (2439 aa) | |||
MUC2 | mucin 2, oligomeric mucus/gel-forming; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer (2817 aa) | |||
MUC15 | mucin 15, cell surface associated; May play a role in the cell adhesion to the extracellular matrix (361 aa) | |||
MUC4 | mucin 4, cell surface associated (5412 aa) | |||
MUC5AC | mucin 5AC, oligomeric mucus/gel-forming (623 aa) | |||
MUC5B | mucin 5B, oligomeric mucus/gel-forming (5762 aa) | |||
MUC12 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium (5335 aa) |