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STRINGSTRING
PRTG PRTG BMP2 BMP2 IGDCC4 IGDCC4 DCC DCC NEO1 NEO1 HFE2 HFE2 FNDC1 FNDC1 IGDCC3 IGDCC3 TMPRSS6 TMPRSS6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
NEO1neogenin 1; May be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. May also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues (1461 aa)
FNDC1fibronectin type III domain containing 1 (1894 aa)
IGDCC4immunoglobulin superfamily, DCC subclass, member 4 (1250 aa)
IGDCC3immunoglobulin superfamily, DCC subclass, member 3 (814 aa)
TMPRSS6transmembrane protease, serine 6 (811 aa)
HFE2hemochromatosis type 2 (juvenile) (426 aa)
BMP2bone morphogenetic protein 2; Induces cartilage and bone formation (396 aa)
PRTGprotogenin; May play a role in anteroposterior axis elongation (By similarity) (1150 aa)
DCCdeleted in colorectal carcinoma; Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene (1447 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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