node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANP32E | RDX | ENSP00000324074 | ENSP00000342830 | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity (By similarity) | radixin; Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane | 0.538 |
ANP32E | RNASEH2B | ENSP00000324074 | ENSP00000337623 | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity (By similarity) | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | 0.564 |
ANP32E | UBC | ENSP00000324074 | ENSP00000344818 | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity (By similarity) | ubiquitin C | 0.960 |
DNAJB1 | RNASEH2B | ENSP00000254322 | ENSP00000337623 | DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | 0.538 |
DNAJB1 | UBC | ENSP00000254322 | ENSP00000344818 | DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP | ubiquitin C | 0.985 |
DNAJB1 | UBQLN2 | ENSP00000254322 | ENSP00000345195 | DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP | ubiquilin 2; Increases the half-life of proteins destined to be degraded by the proteasome; may modulate proteasome-mediated protein degradation | 0.628 |
NRAS | RNASEH2B | ENSP00000358548 | ENSP00000337623 | neuroblastoma RAS viral (v-ras) oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | 0.644 |
NRAS | UBC | ENSP00000358548 | ENSP00000344818 | neuroblastoma RAS viral (v-ras) oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity | ubiquitin C | 0.941 |
RDX | ANP32E | ENSP00000342830 | ENSP00000324074 | radixin; Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity (By similarity) | 0.538 |
RDX | RNASEH2B | ENSP00000342830 | ENSP00000337623 | radixin; Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | 0.506 |
RDX | UBC | ENSP00000342830 | ENSP00000344818 | radixin; Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane | ubiquitin C | 0.985 |
RNASEH2A | RNASEH2B | ENSP00000221486 | ENSP00000337623 | ribonuclease H2, subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | 0.999 |
RNASEH2A | RNASEH2C | ENSP00000221486 | ENSP00000308193 | ribonuclease H2, subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | ribonuclease H2, subunit C; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | 0.999 |
RNASEH2A | UBC | ENSP00000221486 | ENSP00000344818 | ribonuclease H2, subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | ubiquitin C | 0.935 |
RNASEH2B | ANP32E | ENSP00000337623 | ENSP00000324074 | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity (By similarity) | 0.564 |
RNASEH2B | DNAJB1 | ENSP00000337623 | ENSP00000254322 | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP | 0.538 |
RNASEH2B | NRAS | ENSP00000337623 | ENSP00000358548 | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | neuroblastoma RAS viral (v-ras) oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity | 0.644 |
RNASEH2B | RDX | ENSP00000337623 | ENSP00000342830 | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | radixin; Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane | 0.506 |
RNASEH2B | RNASEH2A | ENSP00000337623 | ENSP00000221486 | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | ribonuclease H2, subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | 0.999 |
RNASEH2B | RNASEH2C | ENSP00000337623 | ENSP00000308193 | ribonuclease H2, subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | ribonuclease H2, subunit C; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes | 0.999 |