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KPNA4 | karyopherin alpha 4 (importin alpha 3); Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alph [...] (521 aa) | |||
SPAG17 | sperm associated antigen 17; Seems to be important for the structural integrity of the central apparatus of the sperm axoneme (By similarity) (2223 aa) | |||
SPAG6 | sperm associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility (By similarity) (509 aa) |