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TLE3 TLE3 NDUFAF5 NDUFAF5 APOOL APOOL PIGM PIGM OPA3 OPA3 NAT2 NAT2 CHCHD10 CHCHD10 PRELID1 PRELID1 KIAA0907 KIAA0907 STARD7 STARD7 WBSCR16 WBSCR16 PHYHIPL PHYHIPL TLE1 TLE1 C17orf89 C17orf89
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
NAT2N-acetyltransferase 2 (arylamine N-acetyltransferase) (290 aa)
PRELID1PRELI domain containing 1; May be important for the development of vital and immunocompetent organs (219 aa)
OPA3optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia); May play some role in mitochondrial processes (180 aa)
WBSCR16Williams-Beuren syndrome chromosome region 16 (464 aa)
STARD7StAR-related lipid transfer (START) domain containing 7 (370 aa)
PIGMphosphatidylinositol glycan anchor biosynthesis, class M; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (423 aa)
KIAA0907KIAA0907 (614 aa)
APOOLapolipoprotein O-like (268 aa)
PHYHIPLphytanoyl-CoA 2-hydroxylase interacting protein-like; May play a role in the development of the central system (By similarity) (376 aa)
TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG (770 aa)
NDUFAF5NADH dehydrogenase (ubiquinone) complex I, assembly factor 5; Involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. May have methyltransferase activity (345 aa)
C17orf89chromosome 17 open reading frame 89 (74 aa)
CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 (142 aa)
TLE3transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) (772 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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