node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MARCKSL1 | MRPL30 | ENSP00000362638 | ENSP00000338057 | MARCKS-like 1; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity) | mitochondrial ribosomal protein L30 | 0.644 |
MARCKSL1 | UBC | ENSP00000362638 | ENSP00000344818 | MARCKS-like 1; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity) | ubiquitin C | 0.775 |
MRPL23 | MRPL38 | ENSP00000370930 | ENSP00000308275 | mitochondrial ribosomal protein L23 | mitochondrial ribosomal protein L38 | 0.703 |
MRPL23 | PEBP1 | ENSP00000370930 | ENSP00000261313 | mitochondrial ribosomal protein L23 | phosphatidylethanolamine binding protein 1; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation | 0.662 |
MRPL23 | PEBP4 | ENSP00000370930 | ENSP00000256404 | mitochondrial ribosomal protein L23 | phosphatidylethanolamine-binding protein 4; Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization | 0.662 |
MRPL30 | MARCKSL1 | ENSP00000338057 | ENSP00000362638 | mitochondrial ribosomal protein L30 | MARCKS-like 1; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity) | 0.644 |
MRPL30 | MRPL38 | ENSP00000338057 | ENSP00000308275 | mitochondrial ribosomal protein L30 | mitochondrial ribosomal protein L38 | 0.788 |
MRPL30 | SLC25A3 | ENSP00000338057 | ENSP00000228318 | mitochondrial ribosomal protein L30 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3; Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP) | 0.644 |
MRPL38 | MRPL23 | ENSP00000308275 | ENSP00000370930 | mitochondrial ribosomal protein L38 | mitochondrial ribosomal protein L23 | 0.703 |
MRPL38 | MRPL30 | ENSP00000308275 | ENSP00000338057 | mitochondrial ribosomal protein L38 | mitochondrial ribosomal protein L30 | 0.788 |
MRPL38 | UBC | ENSP00000308275 | ENSP00000344818 | mitochondrial ribosomal protein L38 | ubiquitin C | 0.530 |
PEBP1 | MRPL23 | ENSP00000261313 | ENSP00000370930 | phosphatidylethanolamine binding protein 1; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation | mitochondrial ribosomal protein L23 | 0.662 |
PEBP1 | UBC | ENSP00000261313 | ENSP00000344818 | phosphatidylethanolamine binding protein 1; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation | ubiquitin C | 0.970 |
PEBP4 | MRPL23 | ENSP00000256404 | ENSP00000370930 | phosphatidylethanolamine-binding protein 4; Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization | mitochondrial ribosomal protein L23 | 0.662 |
SLC25A3 | MRPL30 | ENSP00000228318 | ENSP00000338057 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3; Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP) | mitochondrial ribosomal protein L30 | 0.644 |
SLC25A3 | UBC | ENSP00000228318 | ENSP00000344818 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3; Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP) | ubiquitin C | 0.976 |
UBC | MARCKSL1 | ENSP00000344818 | ENSP00000362638 | ubiquitin C | MARCKS-like 1; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity) | 0.775 |
UBC | MRPL38 | ENSP00000344818 | ENSP00000308275 | ubiquitin C | mitochondrial ribosomal protein L38 | 0.530 |
UBC | PEBP1 | ENSP00000344818 | ENSP00000261313 | ubiquitin C | phosphatidylethanolamine binding protein 1; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation | 0.970 |
UBC | SLC25A3 | ENSP00000344818 | ENSP00000228318 | ubiquitin C | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3; Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP) | 0.976 |