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GDE1 | glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity) (331 aa) | |||
AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that mediates the polyubiquitination of a number of proteins such as CD3D, CYP3A4, CFTR and APOB for proteasomal degradation. Component of a VCP/p97- AMFR/gp78 complex that participates in the final step of endoplasmic reticulum-associated degradation (ERAD). The VCP/p97- AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG complex at the ER membrane and initiating ubiquitination of HMGCR. The ubiquitinated HMGCR is then released f [...] (643 aa) | |||
TUSC5 | tumor suppressor candidate 5; May be involved in fat metabolism (By similarity) (177 aa) | |||
BRI3BP | BRI3 binding protein; Involved in tumorigenesis and may function by stabilizing p53/TP53 (251 aa) |