Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IL1F10 | IL1R1 | ENSP00000341794 | ENSP00000233946 | interleukin 1 family, member 10 (theta); Binds soluble IL-1 receptor type 1 | interleukin 1 receptor, type I; Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex | 0.674 |
IL1F10 | IL1RL2 | ENSP00000341794 | ENSP00000264257 | interleukin 1 family, member 10 (theta); Binds soluble IL-1 receptor type 1 | interleukin 1 receptor-like 2; Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B | 0.499 |
IL1F10 | IL36B | ENSP00000341794 | ENSP00000259213 | interleukin 1 family, member 10 (theta); Binds soluble IL-1 receptor type 1 | interleukin 36, beta; Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensins 4 and 103 as well as a number of matrix metalloproteases | 0.722 |
IL1R1 | IL1F10 | ENSP00000233946 | ENSP00000341794 | interleukin 1 receptor, type I; Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex | interleukin 1 family, member 10 (theta); Binds soluble IL-1 receptor type 1 | 0.674 |
IL1RL2 | IL1F10 | ENSP00000264257 | ENSP00000341794 | interleukin 1 receptor-like 2; Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B | interleukin 1 family, member 10 (theta); Binds soluble IL-1 receptor type 1 | 0.499 |
IL1RL2 | IL36A | ENSP00000264257 | ENSP00000259211 | interleukin 1 receptor-like 2; Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B | interleukin 36, alpha | 0.451 |
IL1RL2 | IL36B | ENSP00000264257 | ENSP00000259213 | interleukin 1 receptor-like 2; Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B | interleukin 36, beta; Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensins 4 and 103 as well as a number of matrix metalloproteases | 0.539 |
IL1RL2 | IL36G | ENSP00000264257 | ENSP00000259205 | interleukin 1 receptor-like 2; Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B | interleukin 36, gamma; Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response | 0.561 |
IL36A | IL1RL2 | ENSP00000259211 | ENSP00000264257 | interleukin 36, alpha | interleukin 1 receptor-like 2; Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B | 0.451 |
IL36B | IL1F10 | ENSP00000259213 | ENSP00000341794 | interleukin 36, beta; Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensins 4 and 103 as well as a number of matrix metalloproteases | interleukin 1 family, member 10 (theta); Binds soluble IL-1 receptor type 1 | 0.722 |
IL36B | IL1RL2 | ENSP00000259213 | ENSP00000264257 | interleukin 36, beta; Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensins 4 and 103 as well as a number of matrix metalloproteases | interleukin 1 receptor-like 2; Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B | 0.539 |
IL36G | IL1RL2 | ENSP00000259205 | ENSP00000264257 | interleukin 36, gamma; Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response | interleukin 1 receptor-like 2; Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B | 0.561 |