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TNP1 | transition protein 1 (during histone to protamine replacement); In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins (55 aa) | |||
MED4 | mediator complex subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (270 aa) | |||
SDCBP | syndecan binding protein (syntenin); Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (298 aa) | |||
TEP1 | telomerase-associated protein 1; Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity) (2627 aa) | |||
C1orf35 | chromosome 1 open reading frame 35 (263 aa) | |||
RNPS1 | RNA binding protein S1, serine-rich domain (305 aa) | |||
TM4SF1 | transmembrane 4 L six family member 1 (202 aa) | |||
ARF4 | ADP-ribosylation factor 4; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (180 aa) | |||
SDC2 | syndecan 2; Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity) (201 aa) | |||
EIF1AD | eukaryotic translation initiation factor 1A domain containing; Plays a role into cellular response to oxidative stress. Decreases cell proliferation (165 aa) | |||
PTMS | parathymosin; Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections (102 aa) | |||
FAM133A | family with sequence similarity 133, member A (248 aa) | |||
SDCBP2 | syndecan binding protein (syntenin) 2 (292 aa) | |||
NFASC | neurofascin (1240 aa) | |||
TIFA | TRAF-interacting protein with forkhead-associated domain; Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (184 aa) | |||
CT45A5 | cancer/testis antigen family 45, member A5 (189 aa) | |||
SDC4 | syndecan 4; Cell surface proteoglycan that bears heparan sulfate (198 aa) | |||
NRXN1 | neurexin 1; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity) (1547 aa) |