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LGALS2 | lectin, galactoside-binding, soluble, 2; This protein binds beta-galactoside. Its physiological function is not yet known (132 aa) | |||
TNP1 | transition protein 1 (during histone to protamine replacement); In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins (55 aa) | |||
PRPF38A | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A; May be required for pre-mRNA splicing (Potential) (312 aa) | |||
SDCBP | syndecan binding protein (syntenin); Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (298 aa) | |||
PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa); Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain (231 aa) | |||
ADAP1 | ArfGAP with dual PH domains 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4) (374 aa) | |||
C1orf35 | chromosome 1 open reading frame 35 (263 aa) | |||
NPM2 | nucleophosmin/nucleoplasmin 2; Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization (214 aa) | |||
ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2; Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3’-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP- dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing (482 aa) | |||
TM4SF1 | transmembrane 4 L six family member 1 (202 aa) | |||
ARF4 | ADP-ribosylation factor 4; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (180 aa) | |||
EIF1AD | eukaryotic translation initiation factor 1A domain containing; Plays a role into cellular response to oxidative stress. Decreases cell proliferation (165 aa) | |||
PTMS | parathymosin; Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections (102 aa) | |||
FAM133A | family with sequence similarity 133, member A (248 aa) | |||
SDCBP2 | syndecan binding protein (syntenin) 2 (292 aa) | |||
ZCCHC17 | zinc finger, CCHC domain containing 17 (241 aa) | |||
NFASC | neurofascin (1240 aa) | |||
BEND7 | BEN domain containing 7 (468 aa) | |||
LYAR | Ly1 antibody reactive homolog (mouse) (379 aa) | |||
LGALS14 | lectin, galactoside-binding, soluble, 14 (168 aa) | |||
TIFA | TRAF-interacting protein with forkhead-associated domain; Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (184 aa) | |||
FBXO28 | F-box protein 28; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (By similarity) (368 aa) | |||
CT45A5 | cancer/testis antigen family 45, member A5 (189 aa) | |||
NRXN1 | neurexin 1; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity) (1547 aa) | |||
PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae); Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing (930 aa) | |||
PRR13 | proline rich 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis (148 aa) |