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VDAC1 | voltage-dependent anion channel 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) [...] (283 aa) | |||
C9orf163 | chromosome 9 open reading frame 163 (203 aa) | |||
LRRK1 | leucine-rich repeat kinase 1 (2015 aa) |