10 items (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Your Input:
	ATXN1	ataxin 1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function (815 aa)
	AGPS	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity) (658 aa)
	IQCB1	IQ motif containing B1; Involved in ciliogenesis (By similarity) (598 aa)
	C20orf24	chromosome 20 open reading frame 24 (143 aa)
	UBC	ubiquitin C (685 aa)
	FAR1	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols (515 aa)
	PEX14	peroxisomal biogenesis factor 14; Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17 (377 aa)
	CLN3	ceroid-lipofuscinosis, neuronal 3 (438 aa)
	GNPAT	glyceronephosphate O-acyltransferase (680 aa)
	SMYD3	SET and MYND domain containing 3; Histone methyltransferase. Specifically methylates ’Lys- 4’ and ’Lys-5’ of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5’-CCCTCC-3’ or 5’-GAGGGG-3’ sequences (428 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGPS	FAR1	ENSP00000264167	ENSP00000346874	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	0.932
AGPS	GNPAT	ENSP00000264167	ENSP00000355607	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	glyceronephosphate O-acyltransferase	0.978
AGPS	PEX14	ENSP00000264167	ENSP00000349016	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	peroxisomal biogenesis factor 14; Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17	0.426
AGPS	UBC	ENSP00000264167	ENSP00000344818	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	ubiquitin C	0.825
ATXN1	UBC	ENSP00000244769	ENSP00000344818	ataxin 1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function	ubiquitin C	0.596
C20orf24	UBC	ENSP00000341213	ENSP00000344818	chromosome 20 open reading frame 24	ubiquitin C	0.795
CLN3	UBC	ENSP00000353073	ENSP00000344818	ceroid-lipofuscinosis, neuronal 3	ubiquitin C	0.924
FAR1	AGPS	ENSP00000346874	ENSP00000264167	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	0.932
FAR1	GNPAT	ENSP00000346874	ENSP00000355607	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	glyceronephosphate O-acyltransferase	0.945
FAR1	PEX14	ENSP00000346874	ENSP00000349016	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	peroxisomal biogenesis factor 14; Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17	0.420
FAR1	SMYD3	ENSP00000346874	ENSP00000373637	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	SET and MYND domain containing 3; Histone methyltransferase. Specifically methylates ’Lys- 4’ and ’Lys-5’ of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5’-CCCTCC-3’ or 5’-GAGGGG-3’ sequences	0.481
FAR1	UBC	ENSP00000346874	ENSP00000344818	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	ubiquitin C	0.923
GNPAT	AGPS	ENSP00000355607	ENSP00000264167	glyceronephosphate O-acyltransferase	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	0.978
GNPAT	FAR1	ENSP00000355607	ENSP00000346874	glyceronephosphate O-acyltransferase	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	0.945
GNPAT	UBC	ENSP00000355607	ENSP00000344818	glyceronephosphate O-acyltransferase	ubiquitin C	0.721
IQCB1	UBC	ENSP00000311505	ENSP00000344818	IQ motif containing B1; Involved in ciliogenesis (By similarity)	ubiquitin C	0.671
PEX14	AGPS	ENSP00000349016	ENSP00000264167	peroxisomal biogenesis factor 14; Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	0.426
PEX14	FAR1	ENSP00000349016	ENSP00000346874	peroxisomal biogenesis factor 14; Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	0.420
PEX14	UBC	ENSP00000349016	ENSP00000344818	peroxisomal biogenesis factor 14; Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17	ubiquitin C	0.874
SMYD3	FAR1	ENSP00000373637	ENSP00000346874	SET and MYND domain containing 3; Histone methyltransferase. Specifically methylates ’Lys- 4’ and ’Lys-5’ of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5’-CCCTCC-3’ or 5’-GAGGGG-3’ sequences	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	0.481

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