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GTPBP1 | GTP binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity) (669 aa) | |||
GIF | gastric intrinsic factor (vitamin B synthesis); Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis (417 aa) | |||
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family); Vitamin B12-binding protein. Transports cobalamin into cells (433 aa) | |||
HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2; E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (1572 aa) | |||
CCNE1 | cyclin E1; Essential for the control of the cell cycle at the G1/S (start) transition (410 aa) | |||
NID1 | nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions (1247 aa) | |||
TAPBPL | TAP binding protein-like (468 aa) | |||
BCAM | basal cell adhesion molecule (Lutheran blood group); Laminin alpha-5 receptor. May mediate intracellular signaling (628 aa) | |||
KCTD5 | potassium channel tetramerisation domain containing 5; Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (234 aa) | |||
GTPBP2 | GTP binding protein 2 (602 aa) | |||
CCNE2 | cyclin E2; Essential for the control of the cell cycle at the late G1 and early S phase (404 aa) | |||
EVX2 | even-skipped homeobox 2 (476 aa) | |||
DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization (895 aa) | |||
KCTD2 | potassium channel tetramerisation domain containing 2 (263 aa) | |||
IGSF9B | immunoglobulin superfamily, member 9B (1349 aa) | |||
UBC | ubiquitin C (685 aa) | |||
EGFLAM | EGF-like, fibronectin type III and laminin G domains (1017 aa) | |||
SLAMF7 | SLAM family member 7; Isoform 1 mediates NK cell activation through a SH2D1A- independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion (335 aa) | |||
LRIT1 | leucine-rich repeat, immunoglobulin-like and transmembrane domains 1; Possible role in phototransduction (623 aa) | |||
LYZL2 | lysozyme-like 2 (194 aa) | |||
LYZL1 | lysozyme-like 1 (194 aa) | |||
LRIT3 | leucine-rich repeat, immunoglobulin-like and transmembrane domains 3; Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi (634 aa) | |||
IGSF11 | immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth (431 aa) | |||
KCTD17 | potassium channel tetramerisation domain containing 17 (297 aa) | |||
EVX1 | even-skipped homeobox 1; May play a role in the specification of neuronal cell types (407 aa) | |||
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila); Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development (1651 aa) |