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MYH9 | myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping (1960 aa) | |||
VIM | vimentin (466 aa) | |||
MYH1 | myosin, heavy chain 1, skeletal muscle, adult; Muscle contraction (1939 aa) | |||
MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic; Muscle contraction (1940 aa) | |||
MYH2 | myosin, heavy chain 2, skeletal muscle, adult; Muscle contraction. Required for cytoskeleton organization (By similarity) (1941 aa) | |||
MYH13 | myosin, heavy chain 13, skeletal muscle; Muscle contraction (1938 aa) | |||
MYH4 | myosin, heavy chain 4, skeletal muscle; Muscle contraction (1939 aa) | |||
TMOD1 | tropomodulin 1; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus (359 aa) | |||
MYH14 | myosin, heavy chain 14, non-muscle (2036 aa) | |||
PTPN23 | protein tyrosine phosphatase, non-receptor type 23; May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis (1636 aa) | |||
MYH10 | myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (1976 aa) | |||
CGN | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier (1203 aa) | |||
TCAP | titin-cap; Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk (167 aa) | |||
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (724 aa) | |||
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (854 aa) | |||
UBC | ubiquitin C (685 aa) | |||
MYH7 | myosin, heavy chain 7, cardiac muscle, beta (1935 aa) | |||
MYH6 | myosin, heavy chain 6, cardiac muscle, alpha; Muscle contraction (1939 aa) | |||
MYOM1 | myomesin 1; Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent (1685 aa) | |||
MYBPC2 | myosin binding protein C, fast type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role (1141 aa) | |||
MYBPC1 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role (1171 aa) | |||
DES | desmin (470 aa) | |||
MYH11 | myosin, heavy chain 11, smooth muscle; Muscle contraction (1979 aa) | |||
NEB | nebulin (8525 aa) | |||
MYH8 | myosin, heavy chain 8, skeletal muscle, perinatal; Muscle contraction (1937 aa) | |||
MYBPC3 | myosin binding protein C, cardiac; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role (1274 aa) |