node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MYBPC1 | MYBPC2 | ENSP00000354849 | ENSP00000350332 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin binding protein C, fast type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | 0.917 |
MYBPC1 | MYBPC3 | ENSP00000354849 | ENSP00000442795 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin binding protein C, cardiac; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | 0.902 |
MYBPC1 | MYBPH | ENSP00000354849 | ENSP00000255416 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin binding protein H; Binds to myosin; probably involved in interaction with thick myofilaments in the A-band | 0.549 |
MYBPC1 | MYH1 | ENSP00000354849 | ENSP00000226207 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 1, skeletal muscle, adult; Muscle contraction | 0.632 |
MYBPC1 | MYH10 | ENSP00000354849 | ENSP00000269243 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 | 0.554 |
MYBPC1 | MYH11 | ENSP00000354849 | ENSP00000379616 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 11, smooth muscle; Muscle contraction | 0.549 |
MYBPC1 | MYH13 | ENSP00000354849 | ENSP00000252172 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 13, skeletal muscle; Muscle contraction | 0.615 |
MYBPC1 | MYH14 | ENSP00000354849 | ENSP00000262269 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 14, non-muscle | 0.938 |
MYBPC1 | MYH15 | ENSP00000354849 | ENSP00000273353 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.540 |
MYBPC1 | MYH2 | ENSP00000354849 | ENSP00000245503 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 2, skeletal muscle, adult; Muscle contraction. Required for cytoskeleton organization (By similarity) | 0.553 |
MYBPC1 | MYH3 | ENSP00000354849 | ENSP00000226209 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 3, skeletal muscle, embryonic; Muscle contraction | 0.959 |
MYBPC1 | MYH4 | ENSP00000354849 | ENSP00000255381 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 4, skeletal muscle; Muscle contraction | 0.540 |
MYBPC1 | MYH6 | ENSP00000354849 | ENSP00000348634 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 6, cardiac muscle, alpha; Muscle contraction | 0.929 |
MYBPC1 | MYH7 | ENSP00000354849 | ENSP00000347507 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 7, cardiac muscle, beta | 0.622 |
MYBPC1 | MYH7B | ENSP00000354849 | ENSP00000262873 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 7B, cardiac muscle, beta; Involved in muscle contraction | 0.540 |
MYBPC1 | MYH8 | ENSP00000354849 | ENSP00000384330 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 8, skeletal muscle, perinatal; Muscle contraction | 0.929 |
MYBPC1 | MYH9 | ENSP00000354849 | ENSP00000216181 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping | 0.540 |
MYBPC1 | MYL1 | ENSP00000354849 | ENSP00000307280 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, light chain 1, alkali; skeletal, fast; Regulatory light chain of myosin. Does not bind calcium | 0.926 |
MYBPC1 | MYL3 | ENSP00000354849 | ENSP00000292327 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myosin, light chain 3, alkali; ventricular, skeletal, slow; Regulatory light chain of myosin. Does not bind calcium | 0.912 |
MYBPC1 | MYOM1 | ENSP00000354849 | ENSP00000348821 | myosin binding protein C, slow type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role | myomesin 1; Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent | 0.596 |