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ANKRD54 | ankyrin repeat domain 54; Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation (By similarity) (300 aa) | |||
ASB1 | ankyrin repeat and SOCS box containing 1; May play a role in testis development (By similarity). Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (335 aa) | |||
ANKRD9 | ankyrin repeat domain 9 (317 aa) | |||
ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (300 aa) | |||
TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex- poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequ [...] (1327 aa) | |||
ASB8 | ankyrin repeat and SOCS box containing 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) (288 aa) | |||
SOX2 | SRY (sex determining region Y)-box 2; Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiat [...] (317 aa) | |||
CASKIN2 | CASK interacting protein 2 (1202 aa) | |||
PPP1R27 | protein phosphatase 1, regulatory subunit 27; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes (154 aa) | |||
PIDD | p53-induced death domain protein (910 aa) | |||
ANKRD55 | ankyrin repeat domain 55 (614 aa) | |||
CASKIN1 | CASK interacting protein 1; May link the scaffolding protein CASK to downstream intracellular effectors (By similarity) (1431 aa) | |||
NRARP | NOTCH-regulated ankyrin repeat protein; May play a role in the formation of somites (By similarity) (114 aa) | |||
C15orf38 | chromosome 15 open reading frame 38 (226 aa) | |||
POTEC | POTE ankyrin domain family, member C (542 aa) | |||
ANKRD53 | ankyrin repeat domain 53 (530 aa) | |||
TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex- poly-ADP- ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subseque [...] (1166 aa) | |||
ANKRD22 | ankyrin repeat domain 22 (191 aa) | |||
SOWAHC | sosondowah ankyrin repeat domain family member C (525 aa) | |||
KANK1 | KN motif and ankyrin repeat domains 1; Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell sp [...] (1352 aa) | |||
ENSG00000250021 | C15orf38-AP3S2 readthrough (394 aa) | |||
ASB18 | ankyrin repeat and SOCS box containing 18; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) (466 aa) | |||
POTEI | POTE ankyrin domain family, member I (1075 aa) | |||
ANKRD60 | ankyrin repeat domain 60 (345 aa) | |||
ANKRD63 | ankyrin repeat domain 63 (380 aa) | |||
ANKDD1B | ankyrin repeat and death domain containing 1B (528 aa) |