node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP5C1 | EGFR | ENSP00000349142 | ENSP00000275493 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is cou [...] | epidermal growth factor receptor | 0.595 |
ATP5C1 | ITIH2 | ENSP00000349142 | ENSP00000351190 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is cou [...] | inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes | 0.475 |
ATP5C1 | UBC | ENSP00000349142 | ENSP00000344818 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is cou [...] | ubiquitin C | 0.812 |
EGFR | ATP5C1 | ENSP00000275493 | ENSP00000349142 | epidermal growth factor receptor | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is cou [...] | 0.595 |
EGFR | FN1 | ENSP00000275493 | ENSP00000346839 | epidermal growth factor receptor | fibronectin 1 | 0.468 |
EGFR | UBC | ENSP00000275493 | ENSP00000344818 | epidermal growth factor receptor | ubiquitin C | 0.999 |
FCER1A | ITIH2 | ENSP00000357097 | ENSP00000351190 | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines | inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes | 0.576 |
FN1 | EGFR | ENSP00000346839 | ENSP00000275493 | fibronectin 1 | epidermal growth factor receptor | 0.468 |
FN1 | UBC | ENSP00000346839 | ENSP00000344818 | fibronectin 1 | ubiquitin C | 0.810 |
ITIH2 | ATP5C1 | ENSP00000351190 | ENSP00000349142 | inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is cou [...] | 0.475 |
ITIH2 | FCER1A | ENSP00000351190 | ENSP00000357097 | inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines | 0.576 |
ITIH2 | SPINT2 | ENSP00000351190 | ENSP00000301244 | inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes | serine peptidase inhibitor, Kunitz type, 2; Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa | 0.584 |
SPINT2 | ITIH2 | ENSP00000301244 | ENSP00000351190 | serine peptidase inhibitor, Kunitz type, 2; Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa | inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes | 0.584 |
SPINT2 | UBC | ENSP00000301244 | ENSP00000344818 | serine peptidase inhibitor, Kunitz type, 2; Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa | ubiquitin C | 0.620 |
UBC | ATP5C1 | ENSP00000344818 | ENSP00000349142 | ubiquitin C | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is cou [...] | 0.812 |
UBC | EGFR | ENSP00000344818 | ENSP00000275493 | ubiquitin C | epidermal growth factor receptor | 0.999 |
UBC | FN1 | ENSP00000344818 | ENSP00000346839 | ubiquitin C | fibronectin 1 | 0.810 |
UBC | SPINT2 | ENSP00000344818 | ENSP00000301244 | ubiquitin C | serine peptidase inhibitor, Kunitz type, 2; Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa | 0.620 |